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Compounds That Target LYN

LYN proto-oncogene, Src family tyrosine kinase · 68 compounds in BiohacksAI corpus

LYN (LYN proto-oncogene, Src family tyrosine kinase) is a biological target with 68 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into LYN modulation for therapeutic and biohacking applications.

All 50 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Erlotinib
5.55
confidence
3
Imatinib
5.47
confidence
4
Ibrutinib
4.86
confidence
5
Cabozantinib
4.39
confidence
6
Foretinib
4.34
confidence
7
Tozasertib
4.33
confidence
8
Vandetanib
4.30
confidence
9
Ponatinib
4.26
confidence
10
Ceritinib
4.19
confidence
11
Nilotinib
4.17
confidence
12
Bosutinib
4.08
confidence
13
Doramapimod
4.06
confidence
14
Quizartinib
3.99
confidence
15
Midostaurin
3.85
confidence
16
Brigatinib
3.81
confidence
17
Pazopanib
3.69
confidence
18
Neratinib
3.66
confidence
19
Nintedanib
3.61
confidence
20
Canertinib
3.53
confidence
21
Pelitinib
3.50
confidence
22
Tae 684
3.43
confidence
23
Fedratinib
3.40
confidence
24
Mln 8054
3.33
confidence
25
Saracatinib
3.33
confidence
26
Dabrafenib
3.30
confidence
27
Neflamapimod
3.30
confidence
28
Dovitinib
3.09
confidence
29
At 9283
3.09
confidence
30
Dasatinib Anhydrous
3.09
confidence
31
Lestaurtinib
3.04
confidence
32
Spebrutinib
3.04
confidence
33
Danusertib
2.94
confidence
34
Defosbarasertib
2.89
confidence
35
Barasertib
2.89
confidence
36
R 406
2.83
confidence
37
Cediranib
2.83
confidence
38
Milciclib
2.77
confidence
39
Infigratinib
2.77
confidence
40
Masitinib
2.77
confidence
41
Plx 4720
2.71
confidence
42
Kw 2449
2.64
confidence
43
Tivozanib
2.64
confidence
44
Ast 487
2.56
confidence
45
Atuveciclib
2.56
confidence
46
Raf 265
2.48
confidence
47
Defactinib
2.48
confidence
48
Motesanib
2.48
confidence
49
Cudc 101
2.40
confidence
50
Tak 285
2.40
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for LYN (LYN proto-oncogene, Src family tyrosine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: LYN target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.