Compounds That Target MAP2K2

mitogen-activated protein kinase kinase 2 · 145 compounds in BiohacksAI corpus

MAP2K2 (mitogen-activated protein kinase kinase 2) is a biological target with 145 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MAP2K2 modulation for therapeutic and biohacking applications.

View MAP2K2 target page →UniProt: P36507 ↗

Most Studied Compounds for MAP2K2

Dasatinib

299+

studies

Axitinib

298+

studies

Vemurafenib

298+

studies

Trametinib

296+

studies

Pd98059

studies

All 43 Compounds — Ranked by Evidence

Sb 203580

4.92

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Ruxolitinib

4.23

confidence

Bosutinib

4.08

confidence

Neratinib

3.66

confidence

Sb 202190

3.64

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Mirdametinib

3.18

confidence

Trametinib

296+

studies

3.09

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

Selumetinib

3.09

confidence

Lestaurtinib

3.04

confidence

Ci 1040

2.94

confidence

Defosbarasertib

2.89

confidence

Orantinib

2.89

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Cediranib

2.83

confidence

Pha 665752

2.71

confidence

Plx 4720

2.71

confidence

Kw 2449

2.64

confidence

Linsitinib

2.64

confidence

Cobimetinib

2.64

confidence

Azd 7762

2.30

confidence

Avutometinib

2.30

confidence

Binimetinib

2.30

confidence

Su 014813

2.20

confidence

Amg 900

2.08

confidence

Cep 32496

1.95

confidence

Gsk 1059615

1.95

confidence

Tak 733

1.95

confidence

Pd98059

studies

1.10

confidence

Axitinib

298+

studies

0.69

confidence

Dasatinib

299+

studies

0.69

confidence

Vemurafenib

298+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MAP2K2 (mitogen-activated protein kinase kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MAP2K2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.