BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target MAP3K1

mitogen-activated protein kinase kinase kinase 1 · 27 compounds in BiohacksAI corpus

MAP3K1 (mitogen-activated protein kinase kinase kinase 1) is a biological target with 27 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MAP3K1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for MAP3K1
300+
studies
298+
studies
All 27 Compounds — Ranked by Evidence
1
Erlotinib
5.55
confidence
2
Ponatinib
4.26
confidence
3
Ruxolitinib
4.23
confidence
4
Bosutinib
4.08
confidence
5
Pazopanib
3.69
confidence
6
Regorafenib
3.56
confidence
7
Baricitinib
3.56
confidence
8
Pelitinib
3.50
confidence
9
Tae 684
3.43
confidence
10
Ribociclib
3.26
confidence
11
At 9283
3.09
confidence
12
Lestaurtinib
3.04
confidence
13
Danusertib
2.94
confidence
14
Kw 2449
2.64
confidence
15
Ast 487
2.56
confidence
16
Gsk 461364
2.40
confidence
17
Cudc 101
2.40
confidence
18
Golvatinib
2.20
confidence
19
Rg 547
2.08
confidence
20
Ly 3009120
2.08
confidence
21
Tg100 115
2.08
confidence
22
Cyc 116
2.08
confidence
23
Icotinib
1.79
confidence
24
Pf 03814735
1.79
confidence
25
Osi 632
1.79
confidence
298+
studies
1.10
confidence
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MAP3K1 (mitogen-activated protein kinase kinase kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MAP3K1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.