BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B

Compounds That Target MAP3K3

mitogen-activated protein kinase kinase kinase 3 · 123 compounds in BiohacksAI corpus

MAP3K3 (mitogen-activated protein kinase kinase kinase 3) is a biological target with 123 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MAP3K3 modulation for therapeutic and biohacking applications.

Most Studied Compounds for MAP3K3
1.0k+
studies
300+
studies
300+
studies
298+
studies
298+
studies
298+
studies
298+
studies
200+
studies
86+
studies
All 50 Compounds — Ranked by Evidence
1
Gefitinib
5.67
confidence
2
Erlotinib
5.55
confidence
3
Alvocidib
4.52
confidence
4
Foretinib
4.34
confidence
5
Tozasertib
4.33
confidence
6
Ruxolitinib
4.23
confidence
7
Bosutinib
4.08
confidence
8
Midostaurin
3.85
confidence
9
Neratinib
3.66
confidence
10
Nintedanib
3.61
confidence
11
Canertinib
3.53
confidence
12
Pelitinib
3.50
confidence
13
Tae 684
3.43
confidence
14
Fedratinib
3.40
confidence
15
At 9283
3.09
confidence
16
Lestaurtinib
3.04
confidence
17
Ruboxistaurin
2.94
confidence
18
R 406
2.83
confidence
19
Pha 665752
2.71
confidence
20
Gsk 690693
2.64
confidence
21
Kw 2449
2.64
confidence
22
Motesanib
2.48
confidence
23
Su 014813
2.20
confidence
24
Amg 900
2.08
confidence
25
Pf 03814735
1.79
confidence
26
Ziziphus Jujuba
1.00
confidence
27
Artemisia Argyi
1.00
confidence
28
Artemisia Capillaris
1.00
confidence
29
Ephedra Sinica
1.00
confidence
30
Glycine Max
1.00
confidence
31
Lycopus Lucidus
1.00
confidence
32
Magnolia Biondii
1.00
confidence
33
Morinda Officinalis
1.00
confidence
34
Morus Alba
1.00
confidence
300+
studies
1.00
confidence
36
Panax Notoginseng
1.00
confidence
37
Perilla Frutescens
1.00
confidence
38
Rehmannia Glutinosa
1.00
confidence
498+
studies
1.00
confidence
200+
studies
1.00
confidence
300+
studies
0.69
confidence
298+
studies
0.69
confidence
1.0k+
studies
0.69
confidence
298+
studies
0.69
confidence
298+
studies
0.69
confidence
298+
studies
0.69
confidence
86+
studies
0.69
confidence
48
Achyranthes Bidentata
0.50
confidence
49
Aconitum Carmichaelii
0.50
confidence
50
Agastache Rugosa
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MAP3K3 (mitogen-activated protein kinase kinase kinase 3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MAP3K3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.