BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target MAP4K3

mitogen-activated protein kinase kinase kinase kinase 3 · 42 compounds in BiohacksAI corpus

MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) is a biological target with 42 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MAP4K3 modulation for therapeutic and biohacking applications.

Most Studied Compounds for MAP4K3
299+
studies
298+
studies
298+
studies
All 42 Compounds — Ranked by Evidence
1
Alvocidib
4.52
confidence
2
Foretinib
4.34
confidence
3
Tozasertib
4.33
confidence
4
Vandetanib
4.30
confidence
5
Bosutinib
4.08
confidence
6
Midostaurin
3.85
confidence
7
Pazopanib
3.69
confidence
8
Neratinib
3.66
confidence
9
Nintedanib
3.61
confidence
10
Pelitinib
3.50
confidence
11
Tae 684
3.43
confidence
12
Fedratinib
3.40
confidence
13
Gilteritinib
3.40
confidence
14
Linifanib
3.33
confidence
15
Jnj 7706621
3.09
confidence
16
Dovitinib
3.09
confidence
17
Lestaurtinib
3.04
confidence
18
Pf 03758309
3.00
confidence
19
Ruboxistaurin
2.94
confidence
20
Danusertib
2.94
confidence
21
Cediranib
2.83
confidence
22
R 406
2.83
confidence
23
K 252a
2.83
confidence
24
Milciclib
2.77
confidence
25
Capivasertib
2.77
confidence
26
Crenolanib
2.71
confidence
27
Pha 665752
2.71
confidence
28
Kw 2449
2.64
confidence
29
Linsitinib
2.64
confidence
30
Zotiraciclib
2.56
confidence
31
Ast 487
2.56
confidence
32
Raf 265
2.48
confidence
33
Ripasudil
2.40
confidence
34
Azd 7762
2.30
confidence
35
Su 014813
2.20
confidence
36
Cyc 116
2.08
confidence
298+
studies
1.79
confidence
38
Pf 03814735
1.79
confidence
39
Ucn 01
1.79
confidence
40
Osi 632
1.79
confidence
299+
studies
0.69
confidence
298+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MAP4K3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.