Compounds That Target MDM2

MDM2 proto-oncogene · 87 compounds in BiohacksAI corpus

MDM2 (MDM2 proto-oncogene) is a biological target with 87 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into MDM2 modulation for therapeutic and biohacking applications.

View MDM2 target page →UniProt: Q00987 ↗

Most Studied Compounds for MDM2

Simvastatin

1.0k+

studies

Sertraline

1.0k+

studies

Cycloheximide

300+

studies

Digitoxigenin

300+

studies

Tubercidin

300+

studies

Digoxigenin

300+

studies

Hexachlorophene

300+

studies

Ouabain

300+

studies

Strophanthidin

300+

studies

Ursolic Acid

300+

studies

All 57 Compounds — Ranked by Evidence

Nutlin 3

4.42

confidence

Benzoquinone

2.94

confidence

Sar 405838

2.77

confidence

Hinokiflavone

2.48

confidence

Ganoderic Acid A

2.40

confidence

Digoxin

299+

studies

1.61

confidence

Calcimycin

216+

studies

1.39

confidence

Cycloheximide

300+

studies

1.39

confidence

Cytarabine

297+

studies

1.39

confidence

Digitoxigenin

300+

studies

1.39

confidence

Niclosamideorganic

1.39

confidence

Tubercidin

300+

studies

1.39

confidence

Nisoldipinedrugage

1.10

confidence

Colchinedrugage

1.10

confidence

Demecolcine

246+

studies

1.10

confidence

Digoxigenin

300+

studies

1.10

confidence

Fluspirilene

74+

studies

1.10

confidence

Gedunin

54+

studies

1.10

confidence

Hexachlorophene

300+

studies

1.10

confidence

Lidoflazine

278+

studies

1.10

confidence

Mycophenolic Aciddrugage

1.10

confidence

Nocodazole

215+

studies

1.10

confidence

Ouabain

300+

studies

1.10

confidence

Paxilline

42+

studies

1.10

confidence

Podofilox

14+

studies

1.10

confidence

Rafoxanide

172+

studies

1.10

confidence

Streptonigrin

299+

studies

1.10

confidence

Strophanthidin

300+

studies

1.10

confidence

Trifluridine

295+

studies

1.10

confidence

Tyrphostin 9

studies

1.10

confidence

Vinblastine Sulfate

81+

studies

1.10

confidence

Anisomycin

247+

studies

1.10

confidence

Astemizole

280+

studies

1.10

confidence

Azacitidine

298+

studies

1.10

confidence

Azacytidine

298+

studies

1.10

confidence

Chlorhexidine

299+

studies

1.10

confidence

Ciclopirox Olaminedrugage

1.10

confidence

Cladribinenucleotide

1.10

confidence

Colchicineheterocyclic

1.10

confidence

Crataegus Pinnatifida

1.00

confidence

Nelumbo Nucifera

1.00

confidence

Prunus Persica

1.00

confidence

Rubia Cordifolia

200+

studies

1.00

confidence

Scutellaria Baicalensis

1.00

confidence

Ziziphus Jujuba

1.00

confidence

Chaenomeles Speciosa

1.00

confidence

Simvastatin

1.0k+

studies

0.69

confidence

Ursolic Acid

300+

studies

0.69

confidence

Amethopterin

289+

studies

0.69

confidence

Melphalan

300+

studies

0.69

confidence

Methylene Blue

200+

studies

0.69

confidence

Lovastatin

300+

studies

0.69

confidence

Dinitrochlorobenzene

300+

studies

0.69

confidence

Dihydrorotenone

13+

studies

0.69

confidence

Cardamonin

180+

studies

0.69

confidence

Aripiprazole

298+

studies

0.69

confidence

Sertraline

1.0k+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for MDM2 (MDM2 proto-oncogene). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: MDM2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.