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BiohacksAI/Targets/NOS3/Compounds

Compounds That Target NOS3

nitric oxide synthase 3 · 141 compounds in BiohacksAI corpus

NOS3 (endothelial nitric oxide synthase, eNOS) produces nitric oxide in vascular endothelium, playing a central role in vasodilation, blood pressure regulation, and cardiovascular health. Modulation of NOS3 activity is a target for compounds promoting vascular function, including L-arginine, citrulline, and various polyphenols. The 141 compounds below represent the full scope of NOS3 modulators in the BiohacksAI corpus.

View NOS3 target page →UniProt: P29474 ↗
Most Studied Compounds for NOS3
1
Nitroarginine
300+
studies
2
Epicatechin
300+
studies
3
L-Arginine
300+
studies
4
Arginine
300+
studies
5
Sesamol
293+
studies
6
Bdb Chembl1825168
2+
studies
All 13 Compounds — Ranked by Evidence
1
7 Nitroindazole
2.94
confidence
2
2 Aminopyridine
2.83
confidence
3
L Nio
2.20
confidence
4
Ng Nitroarginine Methyl Esterpeptide
2.08
confidence
5
Gw 274150
1.95
confidence
6
Thiocitrulline
1.95
confidence
7
Nitroarginine
300+
studies
1.79
confidence
8
Ethylisothiourea
1.79
confidence
9
Epicatechin
300+
studies
1.10
confidence
10
L-Arginine
300+
studies
0.69
confidence
11
Arginine
300+
studies
0.69
confidence
12
Sesamol
293+
studies
0.69
confidence
13
Bdb Chembl1825168
2+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for NOS3 (nitric oxide synthase 3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: NOS3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.