BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/NR1H2/Compounds

Compounds That Target NR1H2

nuclear receptor subfamily 1 group H member 2 · 33 compounds in BiohacksAI corpus

NR1H2 (nuclear receptor subfamily 1 group H member 2) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 33 compounds with documented NR1H2 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View NR1H2 target page →UniProt: P55055 ↗
Most Studied Compounds for NR1H2
1
Allium Sativum
500+
studies
2
Desmosterol
300+
studies
3
Panax Ginseng
300+
studies
4
Progesterone
299+
studies
5
Gemfibrozil
297+
studies
6
Luteolin
150+
studies
7
Bdb 3 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthre
2+
studies
8
Bdb 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthrene
2+
studies
All 33 Compounds — Ranked by Evidence
1
T091317
4.47
confidence
2
Ruxolitinib
4.23
confidence
3
Alitretinoin
4.03
confidence
4
Bexarotene
4.03
confidence
5
22r Hydroxycholesterol
2.77
confidence
6
E Guggulsterone
2.40
confidence
7
Cyanidin
2.40
confidence
8
Butylparaben
2.08
confidence
9
Lxr 623
1.95
confidence
10
24s25 Epoxycholesterol
1.95
confidence
11
Desmosterol
300+
studies
1.10
confidence
12
Aloe Vera
1.00
confidence
13
Allium Sativum
500+
studies
1.00
confidence
14
Prunella Vulgaris
1.00
confidence
15
Bdb 3 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthre
2+
studies
0.69
confidence
16
Luteolin
150+
studies
0.69
confidence
17
Bdb 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthrene
2+
studies
0.69
confidence
18
Progesterone
299+
studies
0.69
confidence
19
Gemfibrozil
297+
studies
0.69
confidence
20
Achyranthes Bidentata
0.50
confidence
21
Aconitum Carmichaelii
0.50
confidence
22
Aquilaria Sinensis
0.50
confidence
23
Aucklandia Lappa
0.50
confidence
24
Cimicifuga Heracleifolia
0.50
confidence
25
Leonurus Japonicus
0.50
confidence
26
Lithospermum Erythrorhizon
0.50
confidence
27
Mentha Haplocalyx
0.50
confidence
28
Morinda Officinalis
0.50
confidence
29
Nelumbo Nucifera
0.50
confidence
30
Salvia Miltiorrhiza
0.50
confidence
31
Panax Ginseng
300+
studies
0.50
confidence
32
Ziziphus Jujuba
0.50
confidence
33
Polygonum Cuspidatum
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for NR1H2 (nuclear receptor subfamily 1 group H member 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: NR1H2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.