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BiohacksAI/Targets/NR1H3/Compounds

Compounds That Target NR1H3

nuclear receptor subfamily 1 group H member 3 · 33 compounds in BiohacksAI corpus

NR1H3 (nuclear receptor subfamily 1 group H member 3) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 33 compounds with documented NR1H3 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View NR1H3 target page →UniProt: Q13133 ↗
Most Studied Compounds for NR1H3
1
Allium Sativum
500+
studies
2
Hesperetin
300+
studies
3
Desmosterol
300+
studies
4
Panax Ginseng
300+
studies
5
Bosentan
298+
studies
6
Luteolin
150+
studies
7
Bdb 3 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthre
2+
studies
8
Bdb 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthrene
2+
studies
All 33 Compounds — Ranked by Evidence
1
T091317
4.47
confidence
2
Alitretinoin
4.03
confidence
3
Bexarotene
4.03
confidence
4
22r Hydroxycholesterol
2.77
confidence
5
Cyanidin
2.40
confidence
6
Tryprostatin A
2.30
confidence
7
Lxr 623
1.95
confidence
8
24s25 Epoxycholesterol
1.95
confidence
9
Gsk 4112
1.79
confidence
10
Hesperetin
300+
studies
1.39
confidence
11
Desmosterol
300+
studies
1.10
confidence
12
Prunella Vulgaris
1.00
confidence
13
Luteolin
150+
studies
0.69
confidence
14
Bosentan
298+
studies
0.69
confidence
15
Piericidin Adrugage
0.69
confidence
16
Bdb 3 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthre
2+
studies
0.69
confidence
17
Bdb 4s 4ar 6 Hydroxy 4a Methyl 1 S Methyl 1 2 3 4 4a 9 10 10a Octahydro Phenanthrene
2+
studies
0.69
confidence
18
Achyranthes Bidentata
0.50
confidence
19
Aconitum Carmichaelii
0.50
confidence
20
Allium Sativum
500+
studies
0.50
confidence
21
Aloe Vera
0.50
confidence
22
Aquilaria Sinensis
0.50
confidence
23
Aucklandia Lappa
0.50
confidence
24
Cimicifuga Heracleifolia
0.50
confidence
25
Leonurus Japonicus
0.50
confidence
26
Lithospermum Erythrorhizon
0.50
confidence
27
Mentha Haplocalyx
0.50
confidence
28
Morinda Officinalis
0.50
confidence
29
Nelumbo Nucifera
0.50
confidence
30
Panax Ginseng
300+
studies
0.50
confidence
31
Polygonum Cuspidatum
0.50
confidence
32
Salvia Miltiorrhiza
0.50
confidence
33
Ziziphus Jujuba
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for NR1H3 (nuclear receptor subfamily 1 group H member 3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: NR1H3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.