Compounds That Target NR1H4

nuclear receptor subfamily 1 group H member 4 · 199 compounds in BiohacksAI corpus

NR1H4 (nuclear receptor subfamily 1 group H member 4) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 199 compounds with documented NR1H4 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View NR1H4 target page →UniProt: ADZ17382 ↗

Most Studied Compounds for NR1H4

Atorvastatin

1.0k+

studies

Levothyroxine

994+

studies

Allium Sativum

500+

studies

Genistein

300+

studies

Lithocholic Acid

300+

studies

Ethidium Bromide

300+

studies

Zearalenone

300+

studies

Ethinyl Estradiol

300+

studies

Apigenin

300+

studies

Rotenone

300+

studies

All 55 Compounds — Ranked by Evidence

Raloxifene

4.77

confidence

Chenodiol

4.62

confidence

T091317

4.47

confidence

Nimodipine

4.29

confidence

Andrographolide

4.17

confidence

Chenodeoxycholic Acid

299+

studies

4.13

confidence

Benzbromarone

4.13

confidence

Ivermectin

298+

studies

4.11

confidence

Gw7647

4.11

confidence

Obeticholic Acid

271+

studies

3.99

confidence

Zafirlukast

3.89

confidence

Felodipine

3.85

confidence

6bio

3.50

confidence

Pranlukast

3.30

confidence

Taurursodiol

3.30

confidence

Guggulsterone

2.89

confidence

Sulconazole

2.48

confidence

Vidofludimus

2.48

confidence

E Guggulsterone

2.40

confidence

Ly 255283

2.30

confidence

Archazolid A

1.95

confidence

Genistein

300+

studies

1.95

confidence

Ursodeoxycholic Acid

298+

studies

1.95

confidence

Cholic Acid

299+

studies

1.79

confidence

Lithocholic Acid

300+

studies

1.79

confidence

Ethidium Bromide

300+

studies

1.61

confidence

Zearalenone

300+

studies

1.61

confidence

Resveratrol

298+

studies

1.61

confidence

Ethinyl Estradiol

300+

studies

1.61

confidence

Apigenin

300+

studies

1.39

confidence

Rotenone

300+

studies

1.39

confidence

Colchicineheterocyclic

1.39

confidence

Vinblastine Sulfate

81+

studies

1.10

confidence

Fulvestrant

295+

studies

1.10

confidence

Itraconazole

297+

studies

1.10

confidence

Mometasone Furoate

292+

studies

1.10

confidence

Podofilox

14+

studies

1.10

confidence

Trequinsin Hydrochloride

studies

1.10

confidence

Methylene Blue

200+

studies

1.10

confidence

Chlormadinone Acetate

300+

studies

1.10

confidence

Clotrimazoleheterocyclic

1.10

confidence

Dactinomycin

297+

studies

1.10

confidence

Daunorubicin

298+

studies

1.10

confidence

Decitabine

298+

studies

1.10

confidence

Finasteride

296+

studies

1.10

confidence

Allium Tuberosum

1.00

confidence

Aloe Vera

1.00

confidence

Allium Sativum

500+

studies

1.00

confidence

Agastache Rugosa

1.00

confidence

Achyranthes Bidentata

1.00

confidence

Levothyroxine

994+

studies

0.69

confidence

Chrysinflavonoids

0.69

confidence

Atorvastatin

1.0k+

studies

0.69

confidence

Progesterone

299+

studies

0.69

confidence

Dhea

300+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for NR1H4 (nuclear receptor subfamily 1 group H member 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: NR1H4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.