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BiohacksAI/Targets/NR1I2/Compounds

Compounds That Target NR1I2

nuclear receptor subfamily 1 group I member 2 · 386 compounds in BiohacksAI corpus

NR1I2 (nuclear receptor subfamily 1 group I member 2) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 386 compounds with documented NR1I2 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View NR1I2 target page →UniProt: ADZ17384 ↗
Most Studied Compounds for NR1I2
1
Budesonide
1.0k+
studies
2
Ethinyl Estradiol
300+
studies
3
Apigenin
300+
studies
4
Genistein
300+
studies
5
Lovastatin
300+
studies
6
Estrone
300+
studies
7
Lithocholic Acid
300+
studies
8
Phenylbutazone
300+
studies
9
Daidzein
300+
studies
10
Kaempferol
300+
studies
All 50 Compounds — Ranked by Evidence
1
Raloxifene
4.77
confidence
2
T091317
4.47
confidence
3
Nimodipine
4.29
confidence
4
Diethylstilbestrol
4.06
confidence
5
Dabrafenib
3.30
confidence
6
Guggulsterone
2.89
confidence
7
Coumestrol
2.83
confidence
8
Fipronil
2.64
confidence
9
E Guggulsterone
2.40
confidence
10
Ethinyl Estradiol
300+
studies
2.08
confidence
11
Oxatomide
128+
studies
2.08
confidence
12
Clotrimazoleheterocyclic
1.95
confidence
13
Fulvestrant
295+
studies
1.95
confidence
14
Nisoldipinedrugage
1.95
confidence
15
Reserpine
297+
studies
1.95
confidence
16
Rifaximin
298+
studies
1.95
confidence
17
Lxr 623
1.95
confidence
18
Apigenin
300+
studies
1.79
confidence
19
Genistein
300+
studies
1.79
confidence
20
Resveratrol
298+
studies
1.79
confidence
21
Vitamin A
295+
studies
1.79
confidence
22
Colchicineheterocyclic
1.79
confidence
23
Danazol
298+
studies
1.79
confidence
24
Fluorometholone
299+
studies
1.79
confidence
25
Loratadine
296+
studies
1.79
confidence
26
Lovastatin
300+
studies
1.79
confidence
27
Thiabendazole
299+
studies
1.79
confidence
28
Cintirorgon
1.79
confidence
29
Bosentan
298+
studies
1.61
confidence
30
Celecoxib
295+
studies
1.61
confidence
31
Estrone
300+
studies
1.61
confidence
32
Fluocinolone Acetonide
295+
studies
1.61
confidence
33
Flutamide
298+
studies
1.61
confidence
34
Lithocholic Acid
300+
studies
1.61
confidence
35
Loteprednol Etabonate
213+
studies
1.61
confidence
36
Medroxyprogesterone Acetate
299+
studies
1.61
confidence
37
Phenylbutazone
300+
studies
1.61
confidence
38
Toxaphene
299+
studies
1.61
confidence
39
Troglitazone
299+
studies
1.61
confidence
40
Budesonide
1.0k+
studies
1.39
confidence
41
Daidzein
300+
studies
1.39
confidence
42
Kaempferol
300+
studies
1.39
confidence
43
Vitamin K2
300+
studies
1.39
confidence
44
17 Alpha Hydroxyprogesterone
300+
studies
1.39
confidence
45
17 Alpha Hydroxyprogesterone Caproate
287+
studies
1.39
confidence
46
Alpha Linolenic Acid
300+
studies
1.39
confidence
47
Beclomethasone
300+
studies
1.39
confidence
48
Bromodeoxyuridine
300+
studies
1.39
confidence
49
Candesartan Cilexetil
300+
studies
1.39
confidence
50
Carboxin
174+
studies
1.39
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for NR1I2 (nuclear receptor subfamily 1 group I member 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: NR1I2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.