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Compounds That Target OPRK1

opioid receptor kappa 1 · 180 compounds in BiohacksAI corpus

OPRK1 (opioid receptor kappa 1) is a biological target with 180 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into OPRK1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for OPRK1
300+
studies
299+
studies
297+
studies
295+
studies
All 50 Compounds — Ranked by Evidence
1
Tamoxifen
5.88
confidence
2
Damgo
5.09
confidence
3
Saquinavir
4.98
confidence
299+
studies
4.89
confidence
5
Raloxifene
4.77
confidence
6
Thioridazine
4.52
confidence
7
Nelfinavir
4.51
confidence
8
Amiodarone
4.51
confidence
9
Naltrindole
4.48
confidence
10
Morphinedrugage
4.32
confidence
11
Norbinaltorphimine
4.26
confidence
12
U 69593
4.22
confidence
13
Pimozide
4.19
confidence
14
Diethylstilbestrol
4.06
confidence
15
Naloxoneheterocyclic
4.04
confidence
16
Gentian Violet
4.03
confidence
17
Snc 80
4.01
confidence
18
Loperamide
3.93
confidence
19
Endomorphin 2
3.91
confidence
20
Fluphenazine
3.91
confidence
21
Enkephalin
3.81
confidence
22
Salvinorin A
3.74
confidence
295+
studies
3.69
confidence
24
Nociceptin
3.66
confidence
25
Ritanserin
3.61
confidence
26
Endomorphin 1
3.50
confidence
27
Methadone
3.40
confidence
28
Dermorphin
3.30
confidence
29
Deltorphin C
3.22
confidence
30
Jdtic
3.14
confidence
31
Biphalin
3.04
confidence
32
Butorphan
3.04
confidence
33
Pptn
2.89
confidence
34
Nalmefene
2.89
confidence
35
Falcarindiol
2.83
confidence
36
Nalfurafine
2.77
confidence
37
Volinanserin
2.71
confidence
38
Ici 199441
2.71
confidence
39
Bntx
2.64
confidence
40
Nalbuphineheterocyclic
2.64
confidence
41
Cyclorphan
2.64
confidence
42
Niguldipine
2.56
confidence
43
Nalorphineheterocyclic
2.56
confidence
44
Bisacodyl
2.56
confidence
45
Analog Of Dynorphin A
2.56
confidence
297+
studies
2.48
confidence
47
Nalfurafine Hydrochloride
2.40
confidence
48
Alvimopan
2.40
confidence
49
Penfluridol
2.40
confidence
300+
studies
2.30
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for OPRK1 (opioid receptor kappa 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: OPRK1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.