BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target PAK4

p21 (RAC1) activated kinase 4 · 28 compounds in BiohacksAI corpus

PAK4 (p21 (RAC1) activated kinase 4) is a biological target with 28 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into PAK4 modulation for therapeutic and biohacking applications.

Most Studied Compounds for PAK4
298+
studies
12+
studies
8+
studies
All 28 Compounds — Ranked by Evidence
1
Seliciclib
4.91
confidence
2
Tozasertib
4.33
confidence
3
Ruxolitinib
4.23
confidence
4
Nintedanib
3.61
confidence
5
Tae 684
3.43
confidence
6
Fedratinib
3.40
confidence
7
Purvalanola
3.18
confidence
8
Jnj 7706621
3.09
confidence
9
At 9283
3.09
confidence
10
Lestaurtinib
3.04
confidence
11
Pf 03758309
3.00
confidence
12
R 406
2.83
confidence
13
K 252a
2.83
confidence
14
Pf 00562271
2.77
confidence
15
Crenolanib
2.71
confidence
16
Apitolisib
2.71
confidence
17
Kw 2449
2.64
confidence
18
Gsk 690693
2.64
confidence
19
Defactinib
2.48
confidence
20
Azd 7762
2.30
confidence
21
Azd 1480
2.30
confidence
22
Su 014813
2.20
confidence
23
Cyc 116
2.08
confidence
24
Pf 03814735
1.79
confidence
25
Ucn 01
1.79
confidence
12+
studies
1.10
confidence
8+
studies
1.10
confidence
298+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PAK4 (p21 (RAC1) activated kinase 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PAK4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.