BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/PARP1/Compounds

Compounds That Target PARP1

poly(ADP-ribose) polymerase 1 · 154 compounds in BiohacksAI corpus

PARP1 (poly(ADP-ribose) polymerase 1) is a biological target with 154 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into PARP1 modulation for therapeutic and biohacking applications.

View PARP1 target page →UniProt: P09874 ↗
Most Studied Compounds for PARP1
1
Curcuma Longa
500+
studies
2
Allium Sativum
500+
studies
3
Centella Asiatica
499+
studies
4
Thapsigargin
300+
studies
5
Homoharringtonine
300+
studies
6
Gemcitabine
300+
studies
7
Epirubicin
300+
studies
8
Ginkgo Biloba
299+
studies
9
Teniposide
299+
studies
10
Irinotecan
298+
studies
All 60 Compounds — Ranked by Evidence
1
Olaparib
4.70
confidence
2
Flavone
4.34
confidence
3
Amentoflavone
3.76
confidence
4
Rucaparib
3.58
confidence
5
Veliparib
3.47
confidence
6
Niraparib
3.30
confidence
7
Talazoparib
3.22
confidence
8
Quinazolinone
2.64
confidence
9
Pj34
2.64
confidence
10
Hydroxyfasudil
2.40
confidence
11
Atamparib
2.30
confidence
12
Azd2461
2.20
confidence
13
Benzoylenurea
2.08
confidence
14
2x 121
1.95
confidence
15
Pamiparib
1.79
confidence
16
Phthalazinone
1.79
confidence
17
Luteolin
150+
studies
1.10
confidence
18
Glycyrrhiza Uralensis
1.00
confidence
19
Cnidium Monnieri
1.00
confidence
20
Crataegus Pinnatifida
1.00
confidence
21
Curculigo Orchioides
116+
studies
1.00
confidence
22
Curcuma Longa
500+
studies
1.00
confidence
23
Cuscuta Chinensis
1.00
confidence
24
Cynomorium Songaricum
1.00
confidence
25
Ephedra Sinica
1.00
confidence
26
Eriobotrya Japonica
1.00
confidence
27
Eucommia Ulmoides
1.00
confidence
28
Forsythia Suspensa
1.00
confidence
29
Fritillaria Cirrhosa
1.00
confidence
30
Gastrodia Elata
1.00
confidence
31
Gentiana Macrophylla
1.00
confidence
32
Ginkgo Biloba
299+
studies
1.00
confidence
33
Glycine Max
1.00
confidence
34
Achyranthes Bidentata
1.00
confidence
35
Agastache Rugosa
1.00
confidence
36
Allium Sativum
500+
studies
1.00
confidence
37
Allium Tuberosum
1.00
confidence
38
Aloe Vera
1.00
confidence
39
Anemarrhena Asphodeloides
1.00
confidence
40
Arctium Lappa
1.00
confidence
41
Artemisia Argyi
1.00
confidence
42
Artemisia Capillaris
1.00
confidence
43
Aster Tataricus
1.00
confidence
44
Atractylodes Macrocephala
1.00
confidence
45
Bletilla Striata
1.00
confidence
46
Bupleurum Chinense
1.00
confidence
47
Centella Asiatica
499+
studies
1.00
confidence
48
Chaenomeles Speciosa
1.00
confidence
49
Cimicifuga Heracleifolia
1.00
confidence
50
Citrus Reticulata
1.00
confidence
51
Trabectedin
297+
studies
0.69
confidence
52
Thapsigargin
300+
studies
0.69
confidence
53
Teniposide
299+
studies
0.69
confidence
54
Podofilox
14+
studies
0.69
confidence
55
Nocodazole
215+
studies
0.69
confidence
56
Irinotecan
298+
studies
0.69
confidence
57
Homoharringtonine
300+
studies
0.69
confidence
58
Gemcitabine
300+
studies
0.69
confidence
59
Epirubicin
300+
studies
0.69
confidence
60
Demecolcine
246+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PARP1 (poly(ADP-ribose) polymerase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PARP1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.