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BiohacksAI/Targets/PDE4A/Compounds

Compounds That Target PDE4A

phosphodiesterase 4A · 45 compounds in BiohacksAI corpus

PDE4A (phosphodiesterase 4A) is a biological target with 45 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into PDE4A modulation for therapeutic and biohacking applications.

View PDE4A target page →UniProt: P27815 ↗
Most Studied Compounds for PDE4A
1
Allium Sativum
500+
studies
2
Enoximone
300+
studies
3
Palmitoylethanolamide
300+
studies
4
Vitamin K2
300+
studies
5
Ethynodiol Diacetate
300+
studies
6
Hexachlorophene
300+
studies
7
Methoxypsoralen
300+
studies
8
Panax Ginseng
300+
studies
9
Papaverine
299+
studies
10
Streptonigrin
299+
studies
All 44 Compounds — Ranked by Evidence
1
Sildenafil
4.78
confidence
2
Roflumilast
4.04
confidence
3
Cilomilast
3.71
confidence
4
Piclamilast
3.04
confidence
5
Rolipram
2.83
confidence
6
Cdp840
2.71
confidence
7
Crisaborole
2.71
confidence
8
Ro 201724
2.56
confidence
9
Ibudilast
2.48
confidence
10
Azd 6482
2.30
confidence
11
Sibenadet
2.08
confidence
12
S Rolipram
1.95
confidence
13
Enoximone
300+
studies
1.10
confidence
14
Papaverine
299+
studies
0.69
confidence
15
Streptonigrin
299+
studies
0.69
confidence
16
Sulfisomidine
73+
studies
0.69
confidence
17
Troglitazone
299+
studies
0.69
confidence
18
Ertapenem
299+
studies
0.69
confidence
19
Palmitoylethanolamide
300+
studies
0.69
confidence
20
Vitamin K2
300+
studies
0.69
confidence
21
8 Bromo Cyclic Adenosine Monophosphate
101+
studies
0.69
confidence
22
Anthralin
299+
studies
0.69
confidence
23
Bufexamac
137+
studies
0.69
confidence
24
Cimetidineorganic
0.69
confidence
25
Daptomycin
298+
studies
0.69
confidence
26
Dequalinium
136+
studies
0.69
confidence
27
Disulfiram
297+
studies
0.69
confidence
28
Ethynodiol Diacetate
300+
studies
0.69
confidence
29
Hexachlorophene
300+
studies
0.69
confidence
30
Methoxypsoralen
300+
studies
0.69
confidence
31
Ephedra Sinica
0.50
confidence
32
Forsythia Suspensa
0.50
confidence
33
Morus Alba
0.50
confidence
34
Nelumbo Nucifera
0.50
confidence
35
Panax Ginseng
300+
studies
0.50
confidence
36
Panax Notoginseng
0.50
confidence
37
Piper Nigrum
0.50
confidence
38
Salvia Miltiorrhiza
0.50
confidence
39
Sophora Flavescens
0.50
confidence
40
Curculigo Orchioides
116+
studies
0.50
confidence
41
Bupleurum Chinense
0.50
confidence
42
Apis Mellifera
0.50
confidence
43
Aloe Vera
0.50
confidence
44
Allium Sativum
500+
studies
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PDE4A (phosphodiesterase 4A). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PDE4A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.