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BiohacksAI/Targets/PDE5A/Compounds

Compounds That Target PDE5A

phosphodiesterase 5A · 113 compounds in BiohacksAI corpus

PDE5A (phosphodiesterase 5A) is a biological target with 113 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into PDE5A modulation for therapeutic and biohacking applications.

View PDE5A target page →UniProt: O76074 ↗
Most Studied Compounds for PDE5A
1
Zingiber Officinale
498+
studies
2
Sildenafil Citrate
300+
studies
3
Panax Ginseng
300+
studies
4
Icariin
300+
studies
5
Papaverine
299+
studies
6
Rubia Cordifolia
200+
studies
7
Smilax China
142+
studies
All 50 Compounds — Ranked by Evidence
1
Rolipram
5.12
confidence
2
Sb 203580
4.92
confidence
3
Ly 294002
4.84
confidence
4
Sildenafil
4.78
confidence
5
Alpha Naphthoflavone
4.67
confidence
6
Milrinone
4.39
confidence
7
Palbociclib
4.22
confidence
8
Dipyridamole
4.03
confidence
9
Tadalafil
3.93
confidence
10
Zaprinast
3.81
confidence
11
Isobutylmethylxanthine
3.71
confidence
12
Beta Ccm
3.26
confidence
13
Vardenafil
3.18
confidence
14
Fpl 55712
3.18
confidence
15
Rutaecarpine
3.09
confidence
16
Pptn
2.89
confidence
17
Cilostamide
2.56
confidence
18
Ibudilast
2.48
confidence
19
Sophoraflavanone B
2.48
confidence
20
Icaritin
2.40
confidence
21
Bw A78u
1.95
confidence
22
Sildenafil Citrate
300+
studies
1.39
confidence
23
Agastache Rugosa
1.00
confidence
24
Aloe Vera
1.00
confidence
25
Artemisia Argyi
1.00
confidence
26
Bufo Bufo
1.00
confidence
27
Bupleurum Chinense
1.00
confidence
28
Chaenomeles Speciosa
1.00
confidence
29
Ephedra Sinica
1.00
confidence
30
Epimedium Brevicornum
1.00
confidence
31
Gastrodia Elata
1.00
confidence
32
Glycine Max
1.00
confidence
33
Glycyrrhiza Uralensis
1.00
confidence
34
Morus Alba
1.00
confidence
35
Panax Ginseng
300+
studies
1.00
confidence
36
Panax Notoginseng
1.00
confidence
37
Prunus Armeniaca
1.00
confidence
38
Rubia Cordifolia
200+
studies
1.00
confidence
39
Schisandra Chinensis
1.00
confidence
40
Scutellaria Baicalensis
1.00
confidence
41
Smilax China
142+
studies
1.00
confidence
42
Smilax Glabra
1.00
confidence
43
Sophora Flavescens
1.00
confidence
44
Tussilago Farfara
1.00
confidence
45
Vigna Umbellata
1.00
confidence
46
Zingiber Officinale
498+
studies
1.00
confidence
47
Ziziphus Jujuba
1.00
confidence
48
Icariin
300+
studies
0.69
confidence
49
Papaverine
299+
studies
0.69
confidence
50
Achyranthes Bidentata
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PDE5A (phosphodiesterase 5A). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PDE5A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.