Compounds That Target PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha · 165 compounds in BiohacksAI corpus

PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) is a biological target with 165 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into PIK3CA modulation for therapeutic and biohacking applications.

View PIK3CA target page →UniProt: P42337 ↗

Most Studied Compounds for PIK3CA

Allium Sativum

500+

studies

Rapamycin

300+

studies

Wortmannin

300+

studies

Alpelisib

227+

studies

Ly294002

11+

studies

All 53 Compounds — Ranked by Evidence

Epigalocatechin Gallate

5.40

confidence

Ly 294002

4.84

confidence

Dactolisib

4.25

confidence

Pi 103

4.17

confidence

Idelalisib

4.13

confidence

Bi 2536

4.01

confidence

Romidepsin

3.95

confidence

Midostaurin

3.85

confidence

Catechol

3.76

confidence

Zstk 474

3.56

confidence

Cgs 15943

3.47

confidence

Buparlisib

3.40

confidence

Fedratinib

3.40

confidence

Omipalisib

3.14

confidence

Lestaurtinib

3.04

confidence

Ku 55933

2.94

confidence

Duvelisib

2.94

confidence

Quisinostat

2.94

confidence

Azd 8055

2.89

confidence

Fimepinostat

2.89

confidence

Apitolisib

2.71

confidence

Sapanisertib

2.64

confidence

Pf 04691502

2.64

confidence

Gedatolisib

2.56

confidence

Vistusertib

2.48

confidence

Copanlisib

2.40

confidence

Torin1

2.40

confidence

Azd 7648

2.30

confidence

Bimiralisib

2.30

confidence

Vs 5584

2.30

confidence

Azd 6482

2.30

confidence

Bgt 226 Free Base

2.20

confidence

Ku 0063794

2.20

confidence

Voxtalisib

2.08

confidence

Tg100 115

2.08

confidence

Osi 027

2.08

confidence

Gsk 1059615

1.95

confidence

Pilaralisib

1.95

confidence

Rg 7603

1.95

confidence

Azd 8186

1.79

confidence

Eganelisib

1.79

confidence

Ly294002

11+

studies

1.61

confidence

Pictilisibdrugage

1.10

confidence

Artemisia Capillaris

1.00

confidence

Aloe Vera

1.00

confidence

Apis Mellifera

1.00

confidence

Arctium Lappa

1.00

confidence

Agastache Rugosa

1.00

confidence

Allium Sativum

500+

studies

1.00

confidence

Allium Tuberosum

1.00

confidence

Rapamycin

300+

studies

0.69

confidence

Alpelisib

227+

studies

0.69

confidence

Wortmannin

300+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PIK3CA target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.