BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Targets/POLR1A/Compounds

Compounds That Target POLR1A

DNA-directed RNA polymerase I subunit RPA1 · 77 compounds in BiohacksAI corpus

POLR1A (DNA-directed RNA polymerase I subunit RPA1) is a biological target with 77 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into POLR1A modulation for therapeutic and biohacking applications.

View POLR1A target page →
Most Studied Compounds for POLR1A
1
Allium Sativum
500+
studies
2
Juglans Regia
500+
studies
3
Panax Ginseng
300+
studies
4
Ginkgo Biloba
299+
studies
5
Areca Catechu
199+
studies
6
Smilax China
142+
studies
All 50 Compounds — Ranked by Evidence
1
Molibresib
3.81
confidence
2
Artemisia Argyi
1.00
confidence
3
Artemisia Capillaris
1.00
confidence
4
Bombyx Mori
1.00
confidence
5
Cnidium Monnieri
1.00
confidence
6
Glycine Max
1.00
confidence
7
Glycyrrhiza Uralensis
1.00
confidence
8
Lycopus Lucidus
1.00
confidence
9
Morus Alba
1.00
confidence
10
Panax Ginseng
300+
studies
1.00
confidence
11
Panax Notoginseng
1.00
confidence
12
Perilla Frutescens
1.00
confidence
13
Poria Cocos
1.00
confidence
14
Rehmannia Glutinosa
1.00
confidence
15
Saposhnikovia Divaricata
1.00
confidence
16
Smilax China
142+
studies
1.00
confidence
17
Achyranthes Bidentata
0.50
confidence
18
Allium Fistulosum
0.50
confidence
19
Allium Sativum
500+
studies
0.50
confidence
20
Aloe Vera
0.50
confidence
21
Apis Mellifera
0.50
confidence
22
Arctium Lappa
0.50
confidence
23
Areca Catechu
199+
studies
0.50
confidence
24
Artemisia Annua
0.50
confidence
25
Aster Tataricus
0.50
confidence
26
Atractylodes Macrocephala
0.50
confidence
27
Aucklandia Lappa
0.50
confidence
28
Bupleurum Chinense
0.50
confidence
29
Carthamus Tinctorius
0.50
confidence
30
Cimicifuga Heracleifolia
0.50
confidence
31
Citrus Reticulata
0.50
confidence
32
Coix Lacryma
0.50
confidence
33
Commiphora Myrrha
0.50
confidence
34
Corydalis Yanhusuo
0.50
confidence
35
Crataegus Pinnatifida
0.50
confidence
36
Cuscuta Chinensis
0.50
confidence
37
Dendrobium Nobile
0.50
confidence
38
Ephedra Sinica
0.50
confidence
39
Epimedium Brevicornum
0.50
confidence
40
Eriobotrya Japonica
0.50
confidence
41
Euryale Ferox
0.50
confidence
42
Ginkgo Biloba
299+
studies
0.50
confidence
43
Inula Japonica
0.50
confidence
44
Juglans Regia
500+
studies
0.50
confidence
45
Ligusticum Chuanxiong
0.50
confidence
46
Lilium Lancifolium
0.50
confidence
47
Lobelia Chinensis
0.50
confidence
48
Lonicera Japonica
0.50
confidence
49
Mentha Haplocalyx
0.50
confidence
50
Nelumbo Nucifera
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for POLR1A (DNA-directed RNA polymerase I subunit RPA1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: POLR1A target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.