Compounds That Target PPARG

peroxisome proliferator activated receptor gamma · 245 compounds in BiohacksAI corpus

PPARG (peroxisome proliferator-activated receptor gamma) is a nuclear receptor regulating adipogenesis, insulin sensitivity, and inflammation. It is the molecular target of thiazolidinedione drugs and is also modulated by natural compounds including omega-3 fatty acids, berberine, and certain polyphenols. The 245 compounds with PPARG interactions documented below span a broad range of metabolic and anti-inflammatory applications.

View PPARG target page →UniProt: BAH02283 ↗

Most Studied Compounds for PPARG

Warfarin

1.0k+

studies

Levothyroxine

994+

studies

Thyroxine

300+

studies

Genistein

300+

studies

Rotenone

300+

studies

Troglitazone

299+

studies

Glyburide

298+

studies

Indomethacin

297+

studies

Methylene Blue

200+

studies

Urolithin B

49+

studies

All 50 Compounds — Ranked by Evidence

Pioglitazoneheterocyclic

4.51

confidence

Galangin

4.30

confidence

Pirinixic Acid

4.30

confidence

Telmisartan

4.29

confidence

Liothyronine

4.23

confidence

Gw7647

4.11

confidence

Gw501516

4.09

confidence

Namodenoson

3.95

confidence

Troglitazone

299+

studies

3.91

confidence

Zafirlukast

3.89

confidence

Ciglitazone

3.81

confidence

Magnolol

3.78

confidence

Tanshinone Iia

3.74

confidence

Linolenic Acid

3.33

confidence

Psammaplin A

3.18

confidence

Anacardic Acid

3.09

confidence

Stearic Acid

3.09

confidence

Chelerythrine

3.09

confidence

Tiratricol

3.04

confidence

Dodecanoate

3.04

confidence

Tesaglitazar

3.04

confidence

Decanoic Acid

2.94

confidence

Icosapent

2.83

confidence

Falcarindiol

2.83

confidence

Muraglitazar

2.83

confidence

Cannabigerol

2.71

confidence

Methylene Blue

200+

studies

2.64

confidence

Mli 2

2.64

confidence

Methyleugenol

2.64

confidence

Farglitazar

2.48

confidence

Ragaglitazar

2.48

confidence

E Guggulsterone

2.40

confidence

Levothyroxine

994+

studies

2.30

confidence

Thyroxine

300+

studies

2.30

confidence

Gsk 9578

2.30

confidence

Pseudobaptogenin

2.30

confidence

Amorfrutin A

2.30

confidence

Elafibranor

2.30

confidence

Delta9 Tetrahydrocannabinolic Acid A

2.08

confidence

Tetrac

2.08

confidence

Rosiglitazone Maleate

2.08

confidence

Indomethacin

297+

studies

1.95

confidence

Genistein

300+

studies

1.79

confidence

Warfarin

1.0k+

studies

1.79

confidence

Glyburide

298+

studies

1.79

confidence

Rotenone

300+

studies

1.79

confidence

Urolithin B

49+

studies

1.79

confidence

Gw7845

1.79

confidence

L 796449

1.79

confidence

Reglitazar

1.79

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PPARG (peroxisome proliferator activated receptor gamma). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PPARG target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.