Compounds That Target PRKACA

protein kinase cAMP-activated catalytic subunit alpha · 24 compounds in BiohacksAI corpus

PRKACA (protein kinase cAMP-activated catalytic subunit alpha) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 24 compounds with documented PRKACA interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View PRKACA target page →UniProt: P17612 ↗

Most Studied Compounds for PRKACA

Sphingosine

300+

studies

Ha1077

11+

studies

All 24 Compounds — Ranked by Evidence

Ponatinib

4.26

confidence

Midostaurin

3.85

confidence

Sb 202190

3.64

confidence

Baricitinib

3.56

confidence

Tae 684

3.43

confidence

Gf 109203

3.40

confidence

Bms 777607

3.37

confidence

Linifanib

3.33

confidence

At 9283

3.09

confidence

Lestaurtinib

3.04

confidence

Pf 03758309

3.00

confidence

Ruboxistaurin

2.94

confidence

R 406

2.83

confidence

Capivasertib

2.77

confidence

Gsk 690693

2.64

confidence

Ast 487

2.56

confidence

Balanol

2.30

confidence

Ha1077

11+

studies

2.20

confidence

Y 39983

2.20

confidence

Enzastaurin

2.08

confidence

Uprosertib

1.95

confidence

Afuresertib

1.79

confidence

Sar 407899 Free Base

1.79

confidence

Sphingosine

300+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PRKACA (protein kinase cAMP-activated catalytic subunit alpha). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PRKACA target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.