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Compounds That Target PRKCA

protein kinase C, alpha · 39 compounds in BiohacksAI corpus

PRKCA (protein kinase C, alpha) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 39 compounds with documented PRKCA interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

Most Studied Compounds for PRKCA
300+
studies
298+
studies
297+
studies
All 39 Compounds — Ranked by Evidence
1
Tofacitinib
4.65
confidence
2
Alvocidib
4.52
confidence
3
Ruxolitinib
4.23
confidence
4
Midostaurin
3.85
confidence
5
Abemaciclib
3.66
confidence
6
Baricitinib
3.56
confidence
7
Gilteritinib
3.40
confidence
8
Acetoside
3.40
confidence
9
Gf 109203
3.40
confidence
10
Bisindolylmaleimide Ix
3.14
confidence
11
At 9283
3.09
confidence
12
Pacritinib
3.04
confidence
13
Lestaurtinib
3.04
confidence
14
Hymenialdisine
3.00
confidence
15
Pf 03758309
3.00
confidence
16
Ruboxistaurin
2.94
confidence
17
Go 6976
2.89
confidence
18
K 252a
2.83
confidence
19
Ro 316233
2.83
confidence
20
Staurosporinone
2.77
confidence
21
Sotrastaurin
2.77
confidence
22
Capivasertib
2.77
confidence
23
Apitolisib
2.71
confidence
24
Gsk 690693
2.64
confidence
25
Zotiraciclib
2.56
confidence
26
Bms 754807
2.30
confidence
27
Isoxanthohumol
2.30
confidence
28
Balanol
2.30
confidence
29
Decernotinib
2.20
confidence
30
Y 39983
2.20
confidence
31
Enzastaurin
2.08
confidence
32
Uprosertib
1.95
confidence
33
Sb 242235
1.79
confidence
34
Ucn 01
1.79
confidence
35
Afuresertib
1.79
confidence
298+
studies
0.69
confidence
297+
studies
0.69
confidence
300+
studies
0.69
confidence
39
Myricetinflavonoids
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PRKCA (protein kinase C, alpha). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PRKCA target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.