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Compounds That Target PRKDC

protein kinase, DNA-activated, catalytic subunit · 25 compounds in BiohacksAI corpus

PRKDC (protein kinase, DNA-activated, catalytic subunit) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 25 compounds with documented PRKDC interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

Most Studied Compounds for PRKDC
300+
studies
All 25 Compounds — Ranked by Evidence
1
Ly 294002
4.84
confidence
2
Alpha Naphthoflavone
4.67
confidence
3
Dactolisib
4.25
confidence
4
Trifluoperazine
4.25
confidence
5
Pi 103
4.17
confidence
6
Idelalisib
4.13
confidence
7
Cgs 15943
3.47
confidence
8
Buparlisib
3.40
confidence
9
Omipalisib
3.14
confidence
10
Ku 55933
2.94
confidence
11
Fimepinostat
2.89
confidence
12
Apitolisib
2.71
confidence
13
Isogranulatimide
2.56
confidence
14
Torin1
2.40
confidence
15
Cb 5083
2.40
confidence
16
Berzosertib
2.30
confidence
17
Azd 6482
2.30
confidence
18
Bimiralisib
2.30
confidence
19
Azd 7648
2.30
confidence
20
Osi 027
2.08
confidence
21
Elimusertib
2.08
confidence
22
Ceralasertib
2.08
confidence
23
Pilaralisib
1.95
confidence
24
Eganelisib
1.79
confidence
300+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PRKDC (protein kinase, DNA-activated, catalytic subunit). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PRKDC target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.