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Compounds That Target PRKG1

cGMP-dependent protein kinase 1 · 14 compounds in BiohacksAI corpus

PRKG1 (cGMP-dependent protein kinase 1) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 14 compounds with documented PRKG1 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

All 14 Compounds — Ranked by Evidence
1
Midostaurin
3.85
confidence
2
Nintedanib
3.61
confidence
3
Tae 684
3.43
confidence
4
Fedratinib
3.40
confidence
5
Lestaurtinib
3.04
confidence
6
Pacritinib
3.04
confidence
7
Pf 03758309
3.00
confidence
8
Capivasertib
2.77
confidence
9
Kw 2449
2.64
confidence
10
Gsk 690693
2.64
confidence
11
Balanol
2.30
confidence
12
Ipatasertib
2.20
confidence
13
Enzastaurin
2.08
confidence
14
Sar 407899 Free Base
1.79
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PRKG1 (cGMP-dependent protein kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PRKG1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.