BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/PRKN/Compounds

Compounds That Target PRKN

parkin RBR E3 ubiquitin protein ligase · 108 compounds in BiohacksAI corpus

PRKN (parkin RBR E3 ubiquitin protein ligase) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 108 compounds with documented PRKN interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View PRKN target page →UniProt: BAA25751 ↗
Most Studied Compounds for PRKN
1
Curcuma Longa
500+
studies
2
Portulaca Oleracea
500+
studies
3
Allium Sativum
500+
studies
4
Centella Asiatica
499+
studies
5
Zingiber Officinale
498+
studies
6
Apigenin
300+
studies
7
Panax Ginseng
300+
studies
8
Genistein
300+
studies
9
Hexachlorophene
300+
studies
10
Medroxyprogesterone Acetate
299+
studies
All 50 Compounds — Ranked by Evidence
1
Apigenin
300+
studies
1.10
confidence
2
Kenpaullone
8+
studies
1.10
confidence
3
Agastache Rugosa
1.00
confidence
4
Allium Tuberosum
1.00
confidence
5
Aloe Vera
1.00
confidence
6
Artemisia Argyi
1.00
confidence
7
Atractylodes Macrocephala
1.00
confidence
8
Bufo Bufo
1.00
confidence
9
Bupleurum Chinense
1.00
confidence
10
Centella Asiatica
499+
studies
1.00
confidence
11
Chaenomeles Speciosa
1.00
confidence
12
Cimicifuga Heracleifolia
1.00
confidence
13
Citrus Reticulata
1.00
confidence
14
Curcuma Longa
500+
studies
1.00
confidence
15
Fritillaria Cirrhosa
1.00
confidence
16
Gastrodia Elata
1.00
confidence
17
Morus Alba
1.00
confidence
18
Nelumbo Nucifera
1.00
confidence
19
Panax Ginseng
300+
studies
1.00
confidence
20
Pinellia Ternata
1.00
confidence
21
Poria Cocos
1.00
confidence
22
Portulaca Oleracea
500+
studies
1.00
confidence
23
Rehmannia Glutinosa
1.00
confidence
24
Rubia Cordifolia
200+
studies
1.00
confidence
25
Schisandra Chinensis
1.00
confidence
26
Scutellaria Baicalensis
1.00
confidence
27
Smilax Glabra
1.00
confidence
28
Trichosanthes Kirilowii
1.00
confidence
29
Tussilago Farfara
1.00
confidence
30
Vigna Umbellata
1.00
confidence
31
Zingiber Officinale
498+
studies
1.00
confidence
32
Ziziphus Jujuba
1.00
confidence
33
Genistein
300+
studies
0.69
confidence
34
Amn082
29+
studies
0.69
confidence
35
Hexachlorophene
300+
studies
0.69
confidence
36
Medroxyprogesterone Acetate
299+
studies
0.69
confidence
37
Nitrendipinedrugage
0.69
confidence
38
Aconitum Carmichaelii
0.50
confidence
39
Alisma Plantago
0.50
confidence
40
Allium Sativum
500+
studies
0.50
confidence
41
Apis Mellifera
0.50
confidence
42
Aquilaria Sinensis
0.50
confidence
43
Arctium Lappa
0.50
confidence
44
Areca Catechu
199+
studies
0.50
confidence
45
Artemisia Annua
0.50
confidence
46
Artemisia Capillaris
0.50
confidence
47
Aster Tataricus
0.50
confidence
48
Aucklandia Lappa
0.50
confidence
49
Belamcanda Chinensis
0.50
confidence
50
Bletilla Striata
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PRKN (parkin RBR E3 ubiquitin protein ligase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PRKN target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.