Compounds That Target PRMT5

protein arginine methyltransferase 5 · 96 compounds in BiohacksAI corpus

PRMT5 (protein arginine methyltransferase 5) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 96 compounds with documented PRMT5 interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View PRMT5 target page →UniProt: O14744 ↗

Most Studied Compounds for PRMT5

Allium Sativum

500+

studies

Centella Asiatica

499+

studies

Zingiber Officinale

498+

studies

S Adenosylhomocysteine

300+

studies

Panax Ginseng

300+

studies

S Adenosylmethionine

300+

studies

Ginkgo Biloba

299+

studies

Same

299+

studies

Areca Catechu

199+

studies

Smilax China

142+

studies

All 50 Compounds — Ranked by Evidence

Sinefungin

3.74

confidence

Stilbamidine

2.89

confidence

S Adenosylhomocysteine

300+

studies

1.39

confidence

Allium Sativum

500+

studies

1.00

confidence

Aloe Vera

1.00

confidence

Arctium Lappa

1.00

confidence

Centella Asiatica

499+

studies

1.00

confidence

Cynomorium Songaricum

1.00

confidence

Ephedra Sinica

1.00

confidence

Eucommia Ulmoides

1.00

confidence

Forsythia Suspensa

1.00

confidence

Fritillaria Cirrhosa

1.00

confidence

Ginkgo Biloba

299+

studies

1.00

confidence

Glycine Max

1.00

confidence

Lilium Lancifolium

1.00

confidence

Litchi Chinensis

1.00

confidence

Lobelia Chinensis

1.00

confidence

Lonicera Japonica

1.00

confidence

Morus Alba

1.00

confidence

Nelumbo Nucifera

1.00

confidence

Panax Ginseng

300+

studies

1.00

confidence

Panax Notoginseng

1.00

confidence

Polygonum Cuspidatum

1.00

confidence

Prunus Armeniaca

1.00

confidence

Salvia Miltiorrhiza

1.00

confidence

Sargassum Fusiforme

1.00

confidence

Scutellaria Baicalensis

1.00

confidence

Smilax China

142+

studies

1.00

confidence

Vigna Radiata

1.00

confidence

Vigna Umbellata

1.00

confidence

Zingiber Officinale

498+

studies

1.00

confidence

Same

299+

studies

0.69

confidence

S Adenosylmethionine

300+

studies

0.69

confidence

Achyranthes Bidentata

0.50

confidence

Agastache Rugosa

0.50

confidence

Albizia Julibrissin

0.50

confidence

Alisma Plantago

0.50

confidence

Apis Mellifera

0.50

confidence

Aquilaria Sinensis

0.50

confidence

Areca Catechu

199+

studies

0.50

confidence

Artemisia Annua

0.50

confidence

Artemisia Argyi

0.50

confidence

Artemisia Capillaris

0.50

confidence

Asparagus Cochinchinensis

0.50

confidence

Aster Tataricus

0.50

confidence

Atractylodes Macrocephala

0.50

confidence

Aucklandia Lappa

0.50

confidence

Belamcanda Chinensis

0.50

confidence

Bombyx Mori

0.50

confidence

Bupleurum Chinense

0.50

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for PRMT5 (protein arginine methyltransferase 5). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: PRMT5 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.