Compounds That Target ROS1

ROS proto-oncogene 1, receptor tyrosine kinase · 30 compounds in BiohacksAI corpus

ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase) is a biological target with 30 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into ROS1 modulation for therapeutic and biohacking applications.

View ROS1 target page →UniProt: P08922 ↗

Most Studied Compounds for ROS1

Crizotinib

298+

studies

Axitinib

298+

studies

Afatinib

297+

studies

All 30 Compounds — Ranked by Evidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Ceritinib

4.19

confidence

Midostaurin

3.85

confidence

Brigatinib

3.81

confidence

Pazopanib

3.69

confidence

Nintedanib

3.61

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Mln 8054

3.33

confidence

Crizotinib

298+

studies

3.18

confidence

Entrectinib

3.18

confidence

Alectinib

3.18

confidence

Selitrectinib

3.14

confidence

Lestaurtinib

3.04

confidence

Repotrectinib

3.00

confidence

Ruboxistaurin

2.94

confidence

R 406

2.83

confidence

Infigratinib

2.77

confidence

Hesperadin

2.77

confidence

Pha 665752

2.71

confidence

Ast 487

2.56

confidence

Lorlatinib

2.48

confidence

Entospletinib

2.48

confidence

Bms 754807

2.30

confidence

Rebastinib

2.20

confidence

Asp 3026

2.08

confidence

Afatinib

297+

studies

1.10

confidence

Axitinib

298+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ROS1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.