BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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BiohacksAI/Targets/SHMT2/Compounds

Compounds That Target SHMT2

serine hydroxymethyltransferase 2 · 6 compounds in BiohacksAI corpus

SHMT2 (serine hydroxymethyltransferase 2) is a biological target with 6 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into SHMT2 modulation for therapeutic and biohacking applications.

View SHMT2 target page →UniProt: P34897 ↗
Most Studied Compounds for SHMT2
1
Duloxetine
993+
studies
2
Papaverine
299+
studies
3
Oxaprozin
181+
studies
All 6 Compounds — Ranked by Evidence
1
Methotrexate
6.00
confidence
2
Primaquine
4.91
confidence
3
Pyrvinium
2.48
confidence
4
Duloxetine
993+
studies
0.69
confidence
5
Oxaprozin
181+
studies
0.69
confidence
6
Papaverine
299+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for SHMT2 (serine hydroxymethyltransferase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: SHMT2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.