BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B

Compounds That Target SIGMA

Sigma non-opioid intracellular receptor 1 (human) · 15 compounds in BiohacksAI corpus

SIGMA (Sigma non-opioid intracellular receptor 1 (human)) is a biological target with 15 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into SIGMA modulation for therapeutic and biohacking applications.

Most Studied Compounds for SIGMA
1.0k+
studies
994+
studies
300+
studies
299+
studies
299+
studies
299+
studies
299+
studies
299+
studies
297+
studies
296+
studies
All 15 Compounds — Ranked by Evidence
299+
studies
1.10
confidence
994+
studies
1.10
confidence
1.0k+
studies
1.10
confidence
299+
studies
1.10
confidence
280+
studies
1.10
confidence
299+
studies
1.10
confidence
7
1.10
confidence
294+
studies
1.10
confidence
299+
studies
1.10
confidence
295+
studies
1.10
confidence
211+
studies
1.10
confidence
296+
studies
1.10
confidence
300+
studies
1.10
confidence
297+
studies
1.10
confidence
299+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for SIGMA (Sigma non-opioid intracellular receptor 1 (human)). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: SIGMA target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.