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Compounds That Target SLC6A4

solute carrier family 6 member 4 · 271 compounds in BiohacksAI corpus

SLC6A4 (solute carrier family 6 member 4) is a solute carrier transporter mediating the cellular uptake or efflux of nutrients, drugs, and metabolites. SLC transporters are important for nutrient absorption and drug bioavailability. The 271 compounds below have documented interactions with SLC6A4 from the BiohacksAI BindingDB and PubMed corpus.

Most Studied Compounds for SLC6A4
1.0k+
studies
All 50 Compounds — Ranked by Evidence
1
Tamoxifen
5.88
confidence
2
Clozapine
5.81
confidence
3
Imipramine
5.69
confidence
4
Imatinib
5.47
confidence
5
Desipramine
5.23
confidence
6
Primaquine
4.91
confidence
7
Risperidone
4.89
confidence
8
Raloxifene
4.77
confidence
9
Thioridazine
4.52
confidence
10
Amiodarone
4.51
confidence
11
Olanzapine
4.44
confidence
12
Paroxetine
4.39
confidence
13
Citalopram
4.36
confidence
14
Clomipramine
4.28
confidence
15
Promazine
4.19
confidence
16
Pyrilamine
4.17
confidence
17
Vanoxerine
4.08
confidence
18
Diethylstilbestrol
4.06
confidence
19
Ziprasidone
3.99
confidence
20
Loperamide
3.93
confidence
21
Bupropion
3.93
confidence
22
Fluphenazine
3.91
confidence
23
Molibresib
3.81
confidence
24
Ciglitazone
3.81
confidence
25
Salmeterol
3.76
confidence
26
Nomifensine
3.76
confidence
27
Nefazodone
3.71
confidence
28
Atomoxetine
3.71
confidence
29
Clopidogrel
3.66
confidence
30
Ritanserin
3.61
confidence
31
Tropisetron
3.58
confidence
32
Doxazosin
3.53
confidence
1.0k+
studies
3.50
confidence
34
Doxepin
3.50
confidence
35
Dextroamphetamine
3.40
confidence
36
Dobutamine
3.37
confidence
37
Chlorophenylpiperazine
3.37
confidence
38
Prochlorperazine
3.33
confidence
39
Mazindol
3.30
confidence
40
Methylphenidate
3.30
confidence
41
Desloratadine
3.26
confidence
42
Nisoxetine
3.26
confidence
43
Gsk2879552
3.14
confidence
44
Lorcaserin
3.00
confidence
45
Orphenadrine
2.94
confidence
46
Levopropranolol
2.94
confidence
47
Sibutramine
2.89
confidence
48
Milnacipran
2.89
confidence
49
A 485
2.83
confidence
50
Tenamfetamine
2.83
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for SLC6A4 (solute carrier family 6 member 4). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: SLC6A4 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.