Compounds That Target SYK

spleen associated tyrosine kinase · 359 compounds in BiohacksAI corpus

SYK (spleen associated tyrosine kinase) is a biological target with 359 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into SYK modulation for therapeutic and biohacking applications.

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Most Studied Compounds for SYK

Atorvastatin

1.0k+

studies

Simvastatin

1.0k+

studies

Ouabain

300+

studies

Cycloheximide

300+

studies

Dasatinib

299+

studies

Chlorhexidine

299+

studies

Crizotinib

298+

studies

Amethopterin

289+

studies

Sp600125

117+

studies

All 50 Compounds — Ranked by Evidence

Imatinib

5.47

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Morin

4.28

confidence

Ceritinib

4.19

confidence

Bosutinib

4.08

confidence

Bi 2536

4.01

confidence

Midostaurin

3.85

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Gilteritinib

3.40

confidence

Sulfuretin

3.14

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Lestaurtinib

3.04

confidence

Danusertib

2.94

confidence

R 406

2.83

confidence

K 252a

2.83

confidence

Infigratinib

2.77

confidence

Apitolisib

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Raf 265

2.48

confidence

Entospletinib

2.48

confidence

Tyrphostin 47

2.48

confidence

Calphostin C

2.40

confidence

Dasatinib

299+

studies

2.30

confidence

Azd 7762

2.30

confidence

Berzosertib

2.30

confidence

Rebastinib

2.20

confidence

Cyc 116

2.08

confidence

Fostamatinib

2.08

confidence

Glesatinib

2.08

confidence

Ouabain

300+

studies

1.95

confidence

Cerdulatinib

1.95

confidence

Crizotinib

298+

studies

1.79

confidence

Sp600125

117+

studies

1.79

confidence

Pf 03814735

1.79

confidence

Ucn 01

1.79

confidence

Anilinopyrimidine1

1.79

confidence

Atorvastatin

1.0k+

studies

1.61

confidence

Simvastatin

1.0k+

studies

1.61

confidence

Amethopterin

289+

studies

1.61

confidence

Chlorhexidine

299+

studies

1.61

confidence

Clofarabinenucleotide

1.61

confidence

Colchicineheterocyclic

1.61

confidence

Cycloheximide

300+

studies

1.61

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for SYK (spleen associated tyrosine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: SYK target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.