BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving research platform. New compounds and evidence are added continuously.
B

Compounds That Target TBK1

TANK binding kinase 1 · 35 compounds in BiohacksAI corpus

TBK1 (TANK binding kinase 1) is a biological target with 35 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into TBK1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for TBK1
298+
studies
298+
studies
96+
studies
All 35 Compounds — Ranked by Evidence
1
Erlotinib
5.55
confidence
2
Alvocidib
4.52
confidence
3
Foretinib
4.34
confidence
4
Tozasertib
4.33
confidence
5
Ruxolitinib
4.23
confidence
6
Bosutinib
4.08
confidence
7
Midostaurin
3.85
confidence
8
Silmitasertib
3.78
confidence
9
Nintedanib
3.61
confidence
10
Tae 684
3.43
confidence
11
Fedratinib
3.40
confidence
12
Dovitinib
3.09
confidence
13
At 9283
3.09
confidence
14
Lestaurtinib
3.04
confidence
15
Pacritinib
3.04
confidence
16
Filgotinib
3.04
confidence
17
Adavosertib
3.04
confidence
18
Pf 03758309
3.00
confidence
19
Ruboxistaurin
2.94
confidence
20
Momelotinib
2.89
confidence
21
Orantinib
2.89
confidence
22
R 406
2.83
confidence
23
K 252a
2.83
confidence
24
Milciclib
2.77
confidence
25
Pha 665752
2.71
confidence
26
Kw 2449
2.64
confidence
27
Bx 795
2.40
confidence
28
Su 014813
2.20
confidence
29
Cyc 116
2.08
confidence
30
Cerdulatinib
1.95
confidence
31
Pf 03814735
1.79
confidence
32
Ucn 01
1.79
confidence
96+
studies
1.61
confidence
298+
studies
0.69
confidence
298+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for TBK1 (TANK binding kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: TBK1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.