Compounds That Target TIE1

tyrosine kinase with immunoglobulin like and EGF like domains 1 · 35 compounds in BiohacksAI corpus

TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1) is a biological target with 35 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into TIE1 modulation for therapeutic and biohacking applications.

View TIE1 target page →UniProt: P35590 ↗

Most Studied Compounds for TIE1

Sorafenib

300+

studies

Axitinib

298+

studies

Crizotinib

298+

studies

All 35 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Vandetanib

4.30

confidence

Nilotinib

4.17

confidence

Bosutinib

4.08

confidence

Doramapimod

4.06

confidence

Quizartinib

3.99

confidence

Midostaurin

3.85

confidence

Pazopanib

3.69

confidence

Neratinib

3.66

confidence

Nintedanib

3.61

confidence

Canertinib

3.53

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Linifanib

3.33

confidence

Mln 8054

3.33

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

Lestaurtinib

3.04

confidence

Defosbarasertib

2.89

confidence

R 406

2.83

confidence

Cediranib

2.83

confidence

Pha 665752

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Raf 265

2.48

confidence

Brivanib

2.48

confidence

Gsk 461364

2.40

confidence

Bms 754807

2.30

confidence

Su 014813

2.20

confidence

Sorafenib

300+

studies

1.61

confidence

Axitinib

298+

studies

0.69

confidence

Crizotinib

298+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: TIE1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.