BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target TRPA1

transient receptor potential cation channel, subfamily A, member 1 · 160 compounds in BiohacksAI corpus

TRPA1 (transient receptor potential cation channel, subfamily A, member 1) is a biological target with 160 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into TRPA1 modulation for therapeutic and biohacking applications.

Most Studied Compounds for TRPA1
500+
studies
499+
studies
300+
studies
300+
studies
300+
studies
300+
studies
300+
studies
300+
studies
299+
studies
All 59 Compounds — Ranked by Evidence
1
Diclofenac
5.66
confidence
2
Flufenamic Acid
4.14
confidence
3
Urb 597
4.08
confidence
4
Mefenamic Acid
3.93
confidence
5
Cinnamaldehyde
3.78
confidence
6
Sanguinarium
3.40
confidence
7
Benzyl Isothiocyanate
3.30
confidence
8
Allyl Isothiocyanate
3.18
confidence
9
Phenethylisothiocyanate
3.18
confidence
10
Salirasib
2.94
confidence
11
Cannabinol
2.89
confidence
12
Cannabigerol
2.71
confidence
13
Allicin
2.71
confidence
14
Cannabidivarin
2.56
confidence
15
Cannabichromene
2.48
confidence
16
5 Nitro 2 Phenylpropylaminobenzoic Acid Nppb
2.40
confidence
17
Levomenthol
2.30
confidence
18
Liquiritin
2.20
confidence
19
Tetrahydrocannabivarin
2.20
confidence
20
A 079
2.08
confidence
21
Prostaglandin A1
1.95
confidence
22
Voacangine
1.95
confidence
23
4 Hydroxynon 2 Enal
1.79
confidence
300+
studies
1.79
confidence
279+
studies
1.61
confidence
298+
studies
1.61
confidence
27
Nicotinedrugage
1.61
confidence
300+
studies
1.39
confidence
296+
studies
1.39
confidence
151+
studies
1.39
confidence
100+
studies
1.39
confidence
32
298+
studies
1.39
confidence
300+
studies
1.10
confidence
298+
studies
1.10
confidence
300+
studies
1.10
confidence
299+
studies
1.10
confidence
300+
studies
1.10
confidence
38
Aloe Vera
1.00
confidence
39
Arctium Lappa
1.00
confidence
40
Artemisia Argyi
1.00
confidence
41
Artemisia Capillaris
1.00
confidence
42
Atractylodes Macrocephala
1.00
confidence
43
Bupleurum Chinense
1.00
confidence
44
Carthamus Tinctorius
1.00
confidence
499+
studies
1.00
confidence
46
Chaenomeles Speciosa
1.00
confidence
47
Achyranthes Bidentata
1.00
confidence
48
Agastache Rugosa
1.00
confidence
500+
studies
1.00
confidence
50
Apis Mellifera
1.00
confidence
298+
studies
0.69
confidence
52
Niflumic Acidheterocyclic
0.69
confidence
106+
studies
0.69
confidence
297+
studies
0.69
confidence
246+
studies
0.69
confidence
300+
studies
0.69
confidence
148+
studies
0.69
confidence
58
300+
studies
0.69
confidence
59
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for TRPA1 (transient receptor potential cation channel, subfamily A, member 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: TRPA1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.