Compounds That Target TYK2

tyrosine kinase 2 · 66 compounds in BiohacksAI corpus

TYK2 (tyrosine kinase 2) is a biological target with 66 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into TYK2 modulation for therapeutic and biohacking applications.

View TYK2 target page →UniProt: P29597 ↗

Most Studied Compounds for TYK2

Crizotinib

298+

studies

All 50 Compounds — Ranked by Evidence

Erlotinib

5.55

confidence

Imatinib

5.47

confidence

Sb 203580

4.92

confidence

Tofacitinib

4.65

confidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Tozasertib

4.33

confidence

Ruxolitinib

4.23

confidence

Pi 103

4.17

confidence

Bosutinib

4.08

confidence

Midostaurin

3.85

confidence

Silmitasertib

3.78

confidence

Pazopanib

3.69

confidence

Nintedanib

3.61

confidence

Baricitinib

3.56

confidence

6bio

3.50

confidence

Tae 684

3.43

confidence

Fedratinib

3.40

confidence

Dovitinib

3.09

confidence

Jnj 7706621

3.09

confidence

At 9283

3.09

confidence

Upadacitinib

3.09

confidence

Lestaurtinib

3.04

confidence

Pacritinib

3.04

confidence

Filgotinib

3.04

confidence

Momelotinib

2.89

confidence

R 406

2.83

confidence

Infigratinib

2.77

confidence

Hesperadin

2.77

confidence

Pha 665752

2.71

confidence

Enmd 2076

2.71

confidence

Bms 345541

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Raf 265

2.48

confidence

Defactinib

2.48

confidence

Deucravacitinib

2.48

confidence

Azd 1480

2.30

confidence

Reversine

2.30

confidence

Su 014813

2.20

confidence

Decernotinib

2.20

confidence

Gandotinib

2.20

confidence

Cyc 116

2.08

confidence

Tg100 115

2.08

confidence

Cerdulatinib

1.95

confidence

Itacitinib

1.95

confidence

Delgocitinib

1.95

confidence

Pf 03814735

1.79

confidence

Abrocitinib

1.79

confidence

Crizotinib

298+

studies

1.39

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for TYK2 (tyrosine kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: TYK2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.