BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Compounds That Target TYMS

thymidylate synthetase · 127 compounds in BiohacksAI corpus

TYMS (thymidylate synthetase) is a biological target with 127 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into TYMS modulation for therapeutic and biohacking applications.

Most Studied Compounds for TYMS
500+
studies
500+
studies
499+
studies
499+
studies
300+
studies
299+
studies
299+
studies
297+
studies
297+
studies
295+
studies
All 53 Compounds — Ranked by Evidence
1
Methotrexate
6.00
confidence
2
Raltitrexed
3.58
confidence
299+
studies
3.04
confidence
102+
studies
2.83
confidence
5
Phenolphthalein
2.30
confidence
289+
studies
1.39
confidence
297+
studies
1.10
confidence
8
Perilla Frutescens
1.00
confidence
1.00
confidence
300+
studies
1.00
confidence
11
Panax Notoginseng
1.00
confidence
12
Achyranthes Bidentata
1.00
confidence
13
Agastache Rugosa
1.00
confidence
500+
studies
1.00
confidence
15
Allium Tuberosum
1.00
confidence
16
Aloe Vera
1.00
confidence
17
Apis Mellifera
1.00
confidence
18
Arctium Lappa
1.00
confidence
19
Artemisia Argyi
1.00
confidence
20
Artemisia Capillaris
1.00
confidence
21
Atractylodes Macrocephala
1.00
confidence
22
Bombyx Mori
1.00
confidence
23
Bupleurum Chinense
1.00
confidence
24
Carthamus Tinctorius
1.00
confidence
499+
studies
1.00
confidence
26
Chaenomeles Speciosa
1.00
confidence
27
Citrus Reticulata
1.00
confidence
28
Commiphora Myrrha
1.00
confidence
29
Crataegus Pinnatifida
1.00
confidence
500+
studies
1.00
confidence
31
Cynomorium Songaricum
1.00
confidence
32
Ephedra Sinica
1.00
confidence
33
Eriobotrya Japonica
1.00
confidence
34
Eucommia Ulmoides
1.00
confidence
35
Eupatorium Fortunei
1.00
confidence
499+
studies
1.00
confidence
37
Forsythia Suspensa
1.00
confidence
38
Fritillaria Cirrhosa
1.00
confidence
39
Gastrodia Elata
1.00
confidence
40
Gentiana Macrophylla
1.00
confidence
299+
studies
1.00
confidence
42
Glycine Max
1.00
confidence
43
Glycyrrhiza Uralensis
1.00
confidence
44
Lilium Lancifolium
1.00
confidence
45
Litchi Chinensis
1.00
confidence
46
Lithospermum Erythrorhizon
1.00
confidence
47
Lobelia Chinensis
1.00
confidence
48
Lonicera Japonica
1.00
confidence
49
Magnolia Biondii
1.00
confidence
50
Morus Alba
1.00
confidence
202+
studies
0.69
confidence
295+
studies
0.69
confidence
297+
studies
0.69
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for TYMS (thymidylate synthetase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: TYMS target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.