TYPE 1X-VAULT TIMESTAMPED
Molecular Candidate
Single compound candidates with X-Vault cryptographic proof-of-timestamp. Derived from deterministic compound–target–pathway graph analysis across the BiohacksAI corpus.
METHOD · Graph traversal across compound–target–pathway triples. Scored on novelty, target evidence strength, pathway relevance, and literature gap.
SIGNAL · A substance with documented targets, low literature coverage, and high pathway relevance — understudied relative to its biological footprint.
68 discoveriesX-Vault Merkle chain
ExploratoryEvidence AModerate coverage
GUANAZOLE
Methylation
27
/ 100
Novelty10
Target evidence15
Pathway relevance13
Literature gap11
Coverage
53 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
BUNOLOL
Membrane Trafficking
27
/ 100
Novelty11
Target evidence16
Pathway relevance14
Literature gap12
Coverage
49 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence CVery low coverage
PALMOSTATIN B
Metabolism of nitric oxide: NOS3 activation and regulation
27
/ 100
Novelty11
Target evidence10
Pathway relevance14
Literature gap12
Coverage
2 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
CETOMACROGOL NON-IONIC SURFACTANT OF
Signaling by Rho GTPases
27
/ 100
Novelty14
Target evidence12
Pathway relevance6
Literature gap15
Coverage
72 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
FINGOLIMOD HYDROCHLORIDE
Interleukin-6 signaling
28
/ 100
Novelty15
Target evidence14
Pathway relevance8
Literature gap16
Coverage
56 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
SULFAMETER
GPVI-mediated activation cascade
28
/ 100
Novelty20
Target evidence12
Pathway relevance12
Literature gap21
Coverage
52 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DIHYDROERGOCORNINE
Signaling by GPCR
29
/ 100
Novelty12
Target evidence16
Pathway relevance6
Literature gap9
Coverage
65 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
MEMANTINE AMANTADINE DERIVATIVE THAT HAS SOME DOPAMINERGIC EFFECTS. IT HAS BEEN PROPOSED AS
Neurotransmitter receptors and postsynaptic signal transmission
30
/ 100
Novelty18
Target evidence15
Pathway relevance12
Literature gap14
Coverage
34 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
NIGHT VISION FUNCTION OF
GPVI-mediated activation cascade
31
/ 100
Novelty18
Target evidence15
Pathway relevance14
Literature gap11
Coverage
56 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DOXYLAMINE SUCCINATE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
31
/ 100
Novelty19
Target evidence15
Pathway relevance15
Literature gap11
Coverage
35 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
TOLTERODINE TARTRATE
Signaling by GPCR
32
/ 100
Novelty10
Target evidence12
Pathway relevance8
Literature gap15
Coverage
73 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
SEMUSTINE 4-METHYL DERIVATIVE OF LOMUSTINE; (CCNU).
Signaling by ERBB4
32
/ 100
Novelty18
Target evidence14
Pathway relevance16
Literature gap6
Coverage
97 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
FLUPREDNISOLONE
Signaling by Rho GTPases
32
/ 100
Novelty19
Target evidence15
Pathway relevance17
Literature gap7
Coverage
31 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
D-ASPARTIC ACID
Neurotransmitter release cycle
33
/ 100
Novelty11
Target evidence13
Pathway relevance11
Literature gap12
Coverage
29 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
PRASUGREL HYDROCHLORIDE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
33
/ 100
Novelty15
Target evidence17
Pathway relevance15
Literature gap16
Coverage
44 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
RITODRINE
Potassium Channels
33
/ 100
Novelty16
Target evidence17
Pathway relevance16
Literature gap17
Coverage
87 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
NAVITOCLAX
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
33
/ 100
Novelty19
Target evidence13
Pathway relevance7
Literature gap20
Coverage
83 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence CVery low coverage
M084
Post-translational modification: synthesis of GPI-anchored proteins
34
/ 100
Novelty23
Target evidence18
Pathway relevance12
Literature gap7
Coverage
2 studies
Timestamped
May 21, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DEXAMETHASONE ISONICOTINATE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
34
/ 100
Novelty11
Target evidence18
Pathway relevance12
Literature gap8
Coverage
23 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence CVery low coverage
UROLITHIN D
O-linked glycosylation
35
/ 100
Novelty12
Target evidence18
Pathway relevance15
Literature gap21
Coverage
2 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
1-(5,8-DIHYDRO-1,4-DIHYDROXY-5,8-DIOXO-2-NAPHTHYL)-4-METHYLPENT-3-EN-1-YL CINNAMATE [SUPPLEMENTARY CONCEPT]
Methylation
36
/ 100
Novelty21
Target evidence19
Pathway relevance15
Literature gap9
Coverage
54 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
ETAZOLATE
Methylation
36
/ 100
Novelty12
Target evidence17
Pathway relevance9
Literature gap14
Coverage
66 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
FELBINAC
PIP3 activates AKT signaling
36
/ 100
Novelty13
Target evidence18
Pathway relevance10
Literature gap15
Coverage
31 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
GLUTARAL
Signaling by Rho GTPases
36
/ 100
Novelty17
Target evidence15
Pathway relevance14
Literature gap19
Coverage
42 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
CATECHIN
Interleukin-12 family signaling
37
/ 100
Novelty12
Target evidence16
Pathway relevance10
Literature gap10
Coverage
51 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
PRUNETIN
Signaling by Rho GTPases
37
/ 100
Novelty14
Target evidence18
Pathway relevance12
Literature gap11
Coverage
35 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
LYPRESSIN
Intrinsic Pathway for Apoptosis
37
/ 100
Novelty21
Target evidence18
Pathway relevance8
Literature gap18
Coverage
24 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
TETRACYCLINE
Biosynthesis of DHA-derived SPMs
37
/ 100
Novelty16
Target evidence19
Pathway relevance17
Literature gap10
Coverage
52 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
PROPANTHELINE
Signaling by Rho GTPases
38
/ 100
Novelty24
Target evidence20
Pathway relevance13
Literature gap17
Coverage
73 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
EDETIC ACID
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
38
/ 100
Novelty24
Target evidence20
Pathway relevance14
Literature gap18
Coverage
24 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DICHLORORIBOFURANOSYLBENZIMIDAZOLE
PIP3 activates AKT signaling
39
/ 100
Novelty22
Target evidence15
Pathway relevance17
Literature gap20
Coverage
26 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
AMN082
Signaling by GPCR
39
/ 100
Novelty14
Target evidence20
Pathway relevance11
Literature gap8
Coverage
29 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DEQUALINIUM
Signaling by Rho GTPases
40
/ 100
Novelty15
Target evidence19
Pathway relevance16
Literature gap18
Coverage
46 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
BUFOTENIN
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
40
/ 100
Novelty24
Target evidence21
Pathway relevance14
Literature gap10
Coverage
93 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
UROLITHIN B
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
40
/ 100
Novelty24
Target evidence14
Pathway relevance14
Literature gap10
Coverage
52 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
KN 92 [SUPPLEMENTARY CONCEPT] KN 93 ISOMER;
GPVI-mediated activation cascade
41
/ 100
Novelty23
Target evidence19
Pathway relevance15
Literature gap22
Coverage
26 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DESOXIMETASONE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
41
/ 100
Novelty15
Target evidence17
Pathway relevance9
Literature gap9
Coverage
86 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
TAMARIXETIN
Methylation
41
/ 100
Novelty16
Target evidence18
Pathway relevance9
Literature gap10
Coverage
26 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DIMETHYLPHENYLPIPERAZINIUM IODIDE
HIV Infection
42
/ 100
Novelty14
Target evidence20
Pathway relevance14
Literature gap14
Coverage
33 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
SULINDAC SULFIDE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
42
/ 100
Novelty23
Target evidence21
Pathway relevance14
Literature gap19
Coverage
79 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
METHYLNITRONITROSOGUANIDINE
Signaling by Rho GTPases
42
/ 100
Novelty15
Target evidence19
Pathway relevance10
Literature gap20
Coverage
52 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
FLURANDRENOLONE
Signaling by Rho GTPases
43
/ 100
Novelty17
Target evidence20
Pathway relevance14
Literature gap18
Coverage
65 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE
Aflatoxin activation and detoxification
43
/ 100
Novelty19
Target evidence21
Pathway relevance16
Literature gap19
Coverage
76 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DARAPLADIB [SUPPLEMENTARY CONCEPT]
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
43
/ 100
Novelty22
Target evidence16
Pathway relevance10
Literature gap19
Coverage
44 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
PAXILLINE
Signaling by Interleukins
44
/ 100
Novelty18
Target evidence17
Pathway relevance10
Literature gap23
Coverage
42 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DOXAZOSIN
Potassium Channels
44
/ 100
Novelty13
Target evidence19
Pathway relevance18
Literature gap15
Coverage
24 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
HALCINONIDE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
44
/ 100
Novelty15
Target evidence20
Pathway relevance20
Literature gap16
Coverage
88 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
DIMETHISTERONE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
44
/ 100
Novelty16
Target evidence21
Pathway relevance10
Literature gap18
Coverage
45 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
NYLIDRIN
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
44
/ 100
Novelty17
Target evidence22
Pathway relevance10
Literature gap18
Coverage
90 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
ExploratoryEvidence AModerate coverage
PIRENPERONE
Signaling by ERBB4
44
/ 100
Novelty24
Target evidence19
Pathway relevance13
Literature gap14
Coverage
22 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
DESLANOSIDE DEACETYLLANATOSIDE C.
Signaling by Rho GTPases
45
/ 100
Novelty14
Target evidence18
Pathway relevance12
Literature gap17
Coverage
89 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
CARBAZILQUINONE
Signaling by Rho GTPases
46
/ 100
Novelty15
Target evidence20
Pathway relevance14
Literature gap11
Coverage
48 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
NORTRIPTYLINE
Signaling by Rho GTPases
47
/ 100
Novelty24
Target evidence18
Pathway relevance20
Literature gap21
Coverage
28 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
ELIPRODIL
Signaling by Rho GTPases
47
/ 100
Novelty23
Target evidence22
Pathway relevance15
Literature gap8
Coverage
33 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
FEPRAZONE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
48
/ 100
Novelty18
Target evidence21
Pathway relevance13
Literature gap11
Coverage
63 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
GEDUNIN
Signaling by ERBB2
48
/ 100
Novelty14
Target evidence22
Pathway relevance16
Literature gap13
Coverage
54 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
SCRIPTAID
Interleukin-12 family signaling
48
/ 100
Novelty24
Target evidence23
Pathway relevance16
Literature gap18
Coverage
53 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
PROMAZINE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
49
/ 100
Novelty22
Target evidence17
Pathway relevance11
Literature gap18
Coverage
40 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
NICARDIPINE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
50
/ 100
Novelty25
Target evidence24
Pathway relevance14
Literature gap11
Coverage
94 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
AMLEXANOX
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
50
/ 100
Novelty26
Target evidence23
Pathway relevance19
Literature gap21
Coverage
96 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
ETHYLESTRENOL
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
51
/ 100
Novelty24
Target evidence24
Pathway relevance17
Literature gap9
Coverage
70 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
BENZETHONIUM BACTERICIDAL CATIONIC QUATERNARY AMMONIUM SURFACTANT USED AS
Signaling by ERBB4
51
/ 100
Novelty28
Target evidence22
Pathway relevance11
Literature gap23
Coverage
96 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
PHENOXYBENZAMINE
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
52
/ 100
Novelty20
Target evidence21
Pathway relevance17
Literature gap21
Coverage
21 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
TRIOLIMUS [SUPPLEMENTARY CONCEPT]
Signaling by Rho GTPases
54
/ 100
Novelty24
Target evidence24
Pathway relevance16
Literature gap16
Coverage
33 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
CICLOPIROX
Signaling by Rho GTPases
55
/ 100
Novelty21
Target evidence22
Pathway relevance11
Literature gap24
Coverage
88 studies
Timestamped
May 20, 2026
✓X-Vault sealed
REPORT CONTENTS
→Full mechanism hypothesis
→Complete target mapping
→Pathway network analysis
→Supporting literature PMIDs
Research SignalEvidence AModerate coverage
FLUSPIRILENE
Signaling by Rho GTPases
60
/ 100
Novelty25
Target evidence25
Pathway relevance20
Literature gap25
Coverage
74 studies
Timestamped
May 20, 2026
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Research SignalEvidence AModerate coverage
VINBLASTINE SULFATE
Signaling by Rho GTPases
61
/ 100
Novelty29
Target evidence21
Pathway relevance16
Literature gap15
Coverage
81 studies
Timestamped
May 20, 2026
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Research SignalEvidence AModerate coverage
PICTILISIB
GPVI-mediated activation cascade
66
/ 100
Novelty21
Target evidence25
Pathway relevance19
Literature gap18
Coverage
25 studies
Timestamped
May 20, 2026
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All outputs are computational hypothesis candidates — not experimentally validated discoveries. Deterministic graph analysis · X-Vault cryptographic timestamping · Organiq Sweden AB · Patent pending: EVE-PAT-2026-001