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BiohacksAI/Pathways/AMPK Activation
PATHWAYEnergy Sensing

AMPK Activation

AMP-activated protein kinase — master energy sensor, activates catabolic pathways, inhibits mTOR

2,083 compounds · BiohacksAI corpus

2,083
compounds
Compounds
2,083
Category
Energy Sensing
Pathway ID
AMPK
MeSH Terms
AMP-Activated Protein KinasesAMP Activated Protein KinaseAdenylate KinaseProtein KinasesEnergy MetabolismAdenosine Monophosphate
Top Compounds — AMPK Activation (50 of 2,083)
1
Metformin
1,000
studies
73.4
evidence
2
Ibuprofen
1,000
studies
78.8
evidence
3
Liraglutide
999
studies
76.7
evidence
4
Insulin
1,000
studies
70.5
evidence
5
Salbutamol
297
studies
76.1
evidence
6
Metoprolol
1,000
studies
75.7
evidence
7
Aspirin
1,000
studies
69.5
evidence
8
Azithromycin
1,000
studies
78.3
evidence
9
Budesonide
1,000
studies
80.1
evidence
10
Semaglutide
999
studies
69.9
evidence
11
Atorvastatin
1,000
studies
76.1
evidence
12
Simvastatin
1,000
studies
73.6
evidence
13
Amlodipine
1,000
studies
75.7
evidence
14
Naproxen
1,000
studies
74.8
evidence
15
Prednisolone
1,000
studies
79.5
evidence
16
Sertraline
1,000
studies
76.2
evidence
17
Tramadol
1,000
studies
77.9
evidence
18
Diazepam
999
studies
73.0
evidence
19
Doxycycline
999
studies
76.8
evidence
20
Empagliflozin
996
studies
73.3
evidence
21
Levothyroxine
994
studies
64.3
evidence
22
Duloxetine
993
studies
73.0
evidence
23
Sitagliptin
990
studies
72.1
evidence
24
Montelukast
985
studies
69.1
evidence
25
Lisinopril
904
studies
68.6
evidence
26
Alpha_linolenic_acid
518
studies
55.8
evidence
27
Glycine
300
studies
54.6
evidence
28
Dha
300
studies
62.2
evidence
29
Lysine
299
studies
51.2
evidence
30
Tryptophan
300
studies
55.5
evidence
31
Proline
300
studies
47.2
evidence
32
Curcumin
300
studies
58.0
evidence
33
Bacopa_monnieri
507
studies
40.8
evidence
34
Ribose
300
studies
54.5
evidence
35
Vitamin_c
503
studies
60.8
evidence
36
Folate
297
studies
57.7
evidence
37
Epa
300
studies
64.5
evidence
38
Neuropeptide_y
500
studies
44.2
evidence
39
Galanin
500
studies
43.1
evidence
40
Nelumbo__nucifera
500
studies
39.5
evidence
41
Momordica_charantia
500
studies
38.6
evidence
42
Brassica_campestris
500
studies
40.0
evidence
43
Withania_somnifera
500
studies
37.6
evidence
44
Cynodon_dactylon
500
studies
40.5
evidence
45
Solanum_nigrum
500
studies
36.7
evidence
46
Cajanus_cajan
500
studies
39.9
evidence
47
Hibiscus_sabdariffa
500
studies
41.3
evidence
48
Mangifera_indica
500
studies
38.0
evidence
49
Moringa_oleifera
500
studies
37.8
evidence
50
Prunus_avium
500
studies
42.2
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.