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BiohacksAI/Pathways/DNA Damage & Repair
PATHWAYGenomic Stability

DNA Damage & Repair

Genome integrity maintenance — DNA damage accumulates with age, drives mutation and senescence

564 compounds · BiohacksAI corpus

564
compounds
Compounds
564
Category
Genomic Stability
Pathway ID
DNA_REPAIR
MeSH Terms
DNA RepairDNA DamageDNA-PKPARPDouble-Strand DNA BreaksNucleotide Excision RepairBase Excision Repairp53ATM protein
Top Compounds — DNA Damage & Repair (50 of 564)
1
Paracetamol
1,000
studies
77.1
evidence
2
Lysine
299
studies
51.2
evidence
3
Dha
300
studies
62.2
evidence
4
Ribose
300
studies
54.5
evidence
5
Selenium
299
studies
56.8
evidence
6
Brassica_campestris
500
studies
40.0
evidence
7
Cocos_nucifera
500
studies
41.8
evidence
8
Phoenix__dactylifera
500
studies
38.3
evidence
9
Phoenix_dactylifera
500
studies
38.3
evidence
10
Coriandrum_sativum
499
studies
37.6
evidence
11
Hordeum_vulgare
499
studies
39.9
evidence
12
Tribulus_terrestris
499
studies
41.6
evidence
13
Inositol
300
studies
54.4
evidence
14
Magnesium
293
studies
57.4
evidence
15
Rapamycin
300
studies
55.5
evidence
16
Chlorogenic_acid
483
studies
42.0
evidence
17
Ellagic_acid
475
studies
40.7
evidence
18
Silymarin
300
studies
48.7
evidence
19
Sulforaphane
300
studies
43.7
evidence
20
Astaxanthin
300
studies
45.9
evidence
21
Niacinheterocyclic
448
studies
56.2
evidence
22
Spermidine
241
studies
43.7
evidence
23
Myricetinflavonoids
409
studies
40.2
evidence
24
Garlic_extract
394
studies
46.5
evidence
25
Nicotinamide_riboside
354
studies
44.7
evidence
26
Pyrroloquinoline_quinone
310
studies
38.7
evidence
27
Dna_glycosylases
300
studies
38.5
evidence
28
Dna_repair_enzymes
300
studies
40.3
evidence
29
Pyrimidine_dimers
300
studies
41.6
evidence
30
Thymine_dna_glycosylase
300
studies
41.2
evidence
31
Recq_helicases
300
studies
43.1
evidence
32
Dna_ligases
300
studies
42.3
evidence
33
Dna_helicases
300
studies
43.9
evidence
34
Uracil
300
studies
41.2
evidence
35
Replisomes
300
studies
42.4
evidence
36
Exonucleases
300
studies
42.5
evidence
37
Ribonucleotides
300
studies
42.9
evidence
38
Deoxyribose
300
studies
41.0
evidence
39
Methylnitrosourea
300
studies
35.7
evidence
40
Endonucleases
300
studies
41.5
evidence
41
Poly_adenosine_diphosphate_ribose
300
studies
46.8
evidence
42
Proliferating_cell_nuclear_antigen
300
studies
45.0
evidence
43
Dna_adducts
300
studies
39.5
evidence
44
Shelterin_complex
300
studies
44.3
evidence
45
Thymine
300
studies
42.1
evidence
46
Adenosine_diphosphate_ribose
300
studies
46.3
evidence
47
Wortmannin
300
studies
39.1
evidence
48
Sirtuins
300
studies
44.4
evidence
49
2_acetylaminofluorene
300
studies
37.7
evidence
50
Ethylnitrosourea
300
studies
40.6
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.