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BiohacksAI/Pathways/Inflammaging / NF-κB
PATHWAYInflammation

Inflammaging / NF-κB

Chronic low-grade inflammation associated with aging — NF-κB central mediator

3,670 compounds · BiohacksAI corpus

3,670
compounds
Compounds
3,670
Category
Inflammation
Pathway ID
INFLAMMATION
MeSH Terms
NF-kappa BInflammationInterleukin-6Interleukin-1betaTumor Necrosis Factor-alphaCyclooxygenase 2Anti-Inflammatory AgentsCytokinesInflammasomesNLRP3 Inflammasome
Top Compounds — Inflammaging / NF-κB (50 of 3,670)
1
Metformin
1,000
studies
73.4
evidence
2
Ibuprofen
1,000
studies
78.8
evidence
3
Pembrolizumab
1,000
studies
73.3
evidence
4
Rituximab
1,000
studies
74.1
evidence
5
Liraglutide
999
studies
76.7
evidence
6
Fluoxetine
1,000
studies
75.8
evidence
7
Budesonide
1,000
studies
80.1
evidence
8
Prednisolone
1,000
studies
79.5
evidence
9
Naproxen
1,000
studies
74.8
evidence
10
Aspirin
1,000
studies
69.5
evidence
11
Simvastatin
1,000
studies
73.6
evidence
12
Atorvastatin
1,000
studies
76.1
evidence
13
Azithromycin
1,000
studies
78.3
evidence
14
Salbutamol
297
studies
76.1
evidence
15
Losartan
1,000
studies
75.0
evidence
16
Ciprofloxacin
1,000
studies
73.7
evidence
17
Tramadol
1,000
studies
77.9
evidence
18
Insulin
1,000
studies
70.5
evidence
19
Warfarin
1,000
studies
65.0
evidence
20
Amlodipine
1,000
studies
75.7
evidence
21
Paracetamol
1,000
studies
77.1
evidence
22
Sertraline
1,000
studies
76.2
evidence
23
Amoxicillin
1,000
studies
79.4
evidence
24
Metoprolol
1,000
studies
75.7
evidence
25
Semaglutide
999
studies
69.9
evidence
26
Venlafaxine
1,000
studies
74.1
evidence
27
Trastuzumab
1,000
studies
75.4
evidence
28
Doxycycline
999
studies
76.8
evidence
29
Diazepam
999
studies
73.0
evidence
30
Rivaroxaban
999
studies
74.2
evidence
31
Empagliflozin
996
studies
73.3
evidence
32
Enoxaparin
998
studies
76.4
evidence
33
Pregabalin
996
studies
77.1
evidence
34
Apixaban
997
studies
73.8
evidence
35
Escitalopram
995
studies
74.8
evidence
36
Levothyroxine
994
studies
64.3
evidence
37
Quetiapine
994
studies
73.6
evidence
38
Duloxetine
993
studies
73.0
evidence
39
Sitagliptin
990
studies
72.1
evidence
40
Montelukast
985
studies
69.1
evidence
41
Lisinopril
904
studies
68.6
evidence
42
Alpha_linolenic_acid
518
studies
55.8
evidence
43
Glycine
300
studies
54.6
evidence
44
Dha
300
studies
62.2
evidence
45
Lysine
299
studies
51.2
evidence
46
Tryptophan
300
studies
55.5
evidence
47
Proline
300
studies
47.2
evidence
48
Curcumin
300
studies
58.0
evidence
49
Bacopa_monnieri
507
studies
40.8
evidence
50
Ribose
300
studies
54.5
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.