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B
BiohacksAI/Pathways/Inflammaging / NF-κB
PATHWAYInflammation

Inflammaging / NF-κB

Chronic low-grade inflammation associated with aging — NF-κB central mediator

3,670 compounds · BiohacksAI corpus

3,670
compounds
Compounds
3,670
Category
Inflammation
Pathway ID
INFLAMMATION
MeSH Terms
NF-kappa BInflammationInterleukin-6Interleukin-1betaTumor Necrosis Factor-alphaCyclooxygenase 2Anti-Inflammatory AgentsCytokinesInflammasomesNLRP3 Inflammasome
Top Compounds — Inflammaging / NF-κB (50 of 3,670)
1
Budesonide
1,000
studies
80.1
evidence
2
Prednisolone
1,000
studies
79.5
evidence
3
Naproxen
1,000
studies
74.8
evidence
4
Ibuprofen
1,000
studies
78.8
evidence
5
Aspirin
1,000
studies
69.5
evidence
6
Rituximab
1,000
studies
74.1
evidence
7
Simvastatin
1,000
studies
73.6
evidence
8
Atorvastatin
1,000
studies
76.1
evidence
9
Azithromycin
1,000
studies
78.3
evidence
10
Salbutamol
297
studies
76.1
evidence
11
Losartan
1,000
studies
75.0
evidence
12
Ciprofloxacin
1,000
studies
73.7
evidence
13
Tramadol
1,000
studies
77.9
evidence
14
Insulin
1,000
studies
70.5
evidence
15
Warfarin
1,000
studies
65.0
evidence
16
Amlodipine
1,000
studies
75.7
evidence
17
Paracetamol
1,000
studies
77.1
evidence
18
Fluoxetine
1,000
studies
75.8
evidence
19
Sertraline
1,000
studies
76.2
evidence
20
Amoxicillin
1,000
studies
79.4
evidence
21
Metformin
1,000
studies
73.5
evidence
22
Metoprolol
1,000
studies
75.7
evidence
23
Pembrolizumab
1,000
studies
73.3
evidence
24
Venlafaxine
1,000
studies
74.1
evidence
25
Trastuzumab
1,000
studies
75.4
evidence
26
Doxycycline
999
studies
76.8
evidence
27
Liraglutide
999
studies
76.7
evidence
28
Semaglutide
999
studies
69.9
evidence
29
Diazepam
999
studies
73.0
evidence
30
Rivaroxaban
999
studies
74.2
evidence
31
Enoxaparin
998
studies
76.4
evidence
32
Apixaban
997
studies
73.8
evidence
33
Empagliflozin
996
studies
73.3
evidence
34
Pregabalin
996
studies
77.1
evidence
35
Escitalopram
995
studies
74.8
evidence
36
Levothyroxine
994
studies
64.3
evidence
37
Quetiapine
994
studies
73.6
evidence
38
Duloxetine
993
studies
73.0
evidence
39
Sitagliptin
990
studies
72.1
evidence
40
Montelukast
985
studies
69.1
evidence
41
Lisinopril
904
studies
68.6
evidence
42
Portulaca_oleracea
500
studies
38.3
evidence
43
Psoralea_corylifolia
500
studies
37.1
evidence
44
Terminalia_chebula
500
studies
39.0
evidence
45
Curcuma_longa
500
studies
39.8
evidence
46
Punica_granatum
500
studies
38.3
evidence
47
Cymbopogon_citratus
500
studies
37.4
evidence
48
Hibiscus_sabdariffa
500
studies
41.3
evidence
49
Ocimum_sanctum
500
studies
38.1
evidence
50
Momordica_charantia
500
studies
38.6
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.