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BiohacksAI/Pathways/Mitochondrial Biogenesis
PATHWAYEnergy Sensing

Mitochondrial Biogenesis

Formation of new mitochondria — driven by PGC-1α, AMPK, sirtuins; declines with aging

2,203 compounds · BiohacksAI corpus

2,203
compounds
Compounds
2,203
Category
Energy Sensing
Pathway ID
MITOCHONDRIA
MeSH Terms
MitochondriaMitochondrial BiogenesisPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPGC-1alphaMitochondrial Membrane Transport ProteinsMitochondrial ProteinsMitochondrial DynamicsElectron Transport ChainOxidative Phosphorylation
Top Compounds — Mitochondrial Biogenesis (50 of 2,203)
1
Metformin
1,000
studies
73.4
evidence
2
Fluoxetine
1,000
studies
75.8
evidence
3
Rituximab
1,000
studies
74.1
evidence
4
Simvastatin
1,000
studies
73.6
evidence
5
Atorvastatin
1,000
studies
76.1
evidence
6
Insulin
1,000
studies
70.5
evidence
7
Paracetamol
1,000
studies
77.1
evidence
8
Prednisolone
1,000
studies
79.5
evidence
9
Pregabalin
996
studies
77.1
evidence
10
Levothyroxine
994
studies
64.3
evidence
11
Quetiapine
994
studies
73.6
evidence
12
Sitagliptin
990
studies
72.1
evidence
13
Alpha_linolenic_acid
518
studies
55.8
evidence
14
Glycine
300
studies
54.6
evidence
15
Lysine
299
studies
51.2
evidence
16
Dha
300
studies
62.2
evidence
17
Tryptophan
300
studies
55.5
evidence
18
Proline
300
studies
47.2
evidence
19
Curcumin
300
studies
58.0
evidence
20
Bacopa_monnieri
507
studies
40.8
evidence
21
Ribose
300
studies
54.5
evidence
22
Vitamin_c
503
studies
60.8
evidence
23
Epa
300
studies
64.5
evidence
24
Nelumbo__nucifera
500
studies
39.5
evidence
25
Oryza_sativa
500
studies
37.0
evidence
26
Brassica_campestris
500
studies
40.0
evidence
27
Cucumis_sativus
500
studies
40.0
evidence
28
Withania_somnifera
500
studies
37.6
evidence
29
Solanum_nigrum
500
studies
36.7
evidence
30
Galanin
500
studies
43.1
evidence
31
Cannabis_sativa
500
studies
39.8
evidence
32
Citrus_limon
500
studies
39.0
evidence
33
Eucalyptus_globulus
500
studies
39.6
evidence
34
Hibiscus_sabdariffa
500
studies
41.3
evidence
35
Lepidium_sativum
500
studies
36.5
evidence
36
Neuropeptide_y
500
studies
44.2
evidence
37
Phoenix__dactylifera
500
studies
38.3
evidence
38
Phoenix_dactylifera
500
studies
38.3
evidence
39
Cajanus_cajan
500
studies
39.9
evidence
40
Cocos_nucifera
500
studies
41.8
evidence
41
Crocus_sativus
500
studies
40.6
evidence
42
Cymbopogon_citratus
500
studies
37.4
evidence
43
Mangifera_indica
500
studies
38.0
evidence
44
Momordica_charantia
500
studies
38.6
evidence
45
Moringa_oleifera
500
studies
37.8
evidence
46
Ocimum_sanctum
500
studies
38.1
evidence
47
Prunus_avium
500
studies
42.2
evidence
48
Sesamum_indicum
500
studies
41.6
evidence
49
Terminalia_chebula
500
studies
39.0
evidence
50
Glutathione
300
studies
56.9
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.