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BiohacksAI/Pathways/Oxidative Stress / Nrf2
PATHWAYCellular Defense

Oxidative Stress / Nrf2

ROS management and antioxidant defense — Nrf2/ARE pathway central to cellular resilience

3,333 compounds · BiohacksAI corpus

3,333
compounds
Compounds
3,333
Category
Cellular Defense
Pathway ID
OXIDATIVE_STRESS
MeSH Terms
Oxidative StressReactive Oxygen SpeciesNF-E2-Related Factor 2Nrf2AntioxidantsGlutathioneSuperoxide DismutaseCatalaseHeme Oxygenase-1NADPH Oxidase
Top Compounds — Oxidative Stress / Nrf2 (50 of 3,333)
1
Metformin
1,000
studies
73.4
evidence
2
Liraglutide
999
studies
76.7
evidence
3
Rituximab
1,000
studies
74.1
evidence
4
Simvastatin
1,000
studies
73.6
evidence
5
Losartan
1,000
studies
75.0
evidence
6
Insulin
1,000
studies
70.5
evidence
7
Metoprolol
1,000
studies
75.7
evidence
8
Paracetamol
1,000
studies
77.1
evidence
9
Aspirin
1,000
studies
69.5
evidence
10
Atorvastatin
1,000
studies
76.1
evidence
11
Warfarin
1,000
studies
65.0
evidence
12
Amlodipine
1,000
studies
75.7
evidence
13
Amoxicillin
1,000
studies
79.4
evidence
14
Azithromycin
1,000
studies
78.3
evidence
15
Prednisolone
1,000
studies
79.5
evidence
16
Salbutamol
297
studies
76.1
evidence
17
Semaglutide
999
studies
69.9
evidence
18
Venlafaxine
1,000
studies
74.1
evidence
19
Doxycycline
999
studies
76.8
evidence
20
Diazepam
999
studies
73.0
evidence
21
Empagliflozin
996
studies
73.3
evidence
22
Pregabalin
996
studies
77.1
evidence
23
Escitalopram
995
studies
74.8
evidence
24
Levothyroxine
994
studies
64.3
evidence
25
Duloxetine
993
studies
73.0
evidence
26
Sitagliptin
990
studies
72.1
evidence
27
Montelukast
985
studies
69.1
evidence
28
Lisinopril
904
studies
68.6
evidence
29
Alpha_linolenic_acid
518
studies
55.8
evidence
30
Glycine
300
studies
54.6
evidence
31
Dha
300
studies
62.2
evidence
32
Lysine
299
studies
51.2
evidence
33
Tryptophan
300
studies
55.5
evidence
34
Proline
300
studies
47.2
evidence
35
Curcumin
300
studies
58.0
evidence
36
Vitamin_b12
508
studies
60.4
evidence
37
Bacopa_monnieri
507
studies
40.8
evidence
38
Ribose
300
studies
54.5
evidence
39
Vitamin_c
503
studies
60.8
evidence
40
Folate
297
studies
57.7
evidence
41
Selenium
299
studies
56.8
evidence
42
Epa
300
studies
64.5
evidence
43
Hibiscus_sabdariffa
500
studies
41.3
evidence
44
Moringa_oleifera
500
studies
37.8
evidence
45
Ocimum_sanctum
500
studies
38.1
evidence
46
Punica_granatum
500
studies
38.3
evidence
47
Nelumbo__nucifera
500
studies
39.5
evidence
48
Terminalia_chebula
500
studies
39.0
evidence
49
Crocus_sativus
500
studies
40.6
evidence
50
Phoenix__dactylifera
500
studies
38.3
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.