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BiohacksAI/Pathways/Cellular Senescence
PATHWAYCellular Aging

Cellular Senescence

Permanent cell cycle arrest — senescent cells accumulate with age, drive inflammaging via SASP

1,484 compounds · BiohacksAI corpus

1,484
compounds
Compounds
1,484
Category
Cellular Aging
Pathway ID
SENESCENCE
MeSH Terms
Cellular SenescenceCell AgingSenescence-Associated Secretory PhenotypeCyclin-Dependent Kinase Inhibitor p21Tumor Suppressor Protein p53Cyclin-Dependent Kinase Inhibitor p16beta-Galactosidase
Top Compounds — Cellular Senescence (50 of 1,484)
1
Pembrolizumab
1,000
studies
73.3
evidence
2
Rituximab
1,000
studies
74.1
evidence
3
Atorvastatin
1,000
studies
76.1
evidence
4
Budesonide
1,000
studies
80.1
evidence
5
Insulin
1,000
studies
70.5
evidence
6
Prednisolone
1,000
studies
79.5
evidence
7
Trastuzumab
1,000
studies
75.4
evidence
8
Empagliflozin
996
studies
73.3
evidence
9
Alpha_linolenic_acid
518
studies
55.8
evidence
10
Glycine
300
studies
54.6
evidence
11
Lysine
299
studies
51.2
evidence
12
Proline
300
studies
47.2
evidence
13
Vitamin_b12
508
studies
60.4
evidence
14
Bacopa_monnieri
507
studies
40.8
evidence
15
Selenium
299
studies
56.8
evidence
16
Brassica_campestris
500
studies
40.0
evidence
17
Solanum_nigrum
500
studies
36.7
evidence
18
Withania_somnifera
500
studies
37.6
evidence
19
Azadirachta_indica
500
studies
37.0
evidence
20
Galanin
500
studies
43.1
evidence
21
Momordica_charantia
500
studies
38.6
evidence
22
Neuropeptide_y
500
studies
44.2
evidence
23
Ocimum_sanctum
500
studies
38.1
evidence
24
Phoenix__dactylifera
500
studies
38.3
evidence
25
Phoenix_dactylifera
500
studies
38.3
evidence
26
Prunus_avium
500
studies
42.2
evidence
27
Zinc
297
studies
58.1
evidence
28
Cajanus_cajan
500
studies
39.9
evidence
29
Cannabis_sativa
500
studies
39.8
evidence
30
Cucumis_melo
500
studies
41.4
evidence
31
Cucumis_sativus
500
studies
40.0
evidence
32
Cynodon_dactylon
500
studies
40.5
evidence
33
Eucalyptus_globulus
500
studies
39.6
evidence
34
Hibiscus_sabdariffa
500
studies
41.3
evidence
35
Nelumbo__nucifera
500
studies
39.5
evidence
36
Tinospora_cordifolia
499
studies
38.1
evidence
37
Glutathione
300
studies
56.9
evidence
38
Lens_culinaris
499
studies
43.8
evidence
39
Trigonella_foenum
499
studies
39.0
evidence
40
Boswellia_serrata
499
studies
47.2
evidence
41
Coriandrum_sativum
499
studies
37.6
evidence
42
Nigella_sativa
499
studies
41.7
evidence
43
Linum_usitatissimum
499
studies
41.4
evidence
44
Ricinus_communis
499
studies
37.5
evidence
45
Resveratrol
298
studies
52.2
evidence
46
Progesterone
299
studies
60.4
evidence
47
L_carnitine
495
studies
62.4
evidence
48
Ergosterol
300
studies
40.3
evidence
49
Boron
300
studies
41.4
evidence
50
Rapamycin
300
studies
55.5
evidence

Data from PubMed, BindingDB, and Reactome. Not medical advice.