PATHWAYCellular Aging
Cellular Senescence
Permanent cell cycle arrest — senescent cells accumulate with age, drive inflammaging via SASP
1,484 compounds · BiohacksAI corpus
1,484
compounds
Compounds
1,484
Category
Cellular Aging
Pathway ID
SENESCENCE
MeSH Terms
Cellular SenescenceCell AgingSenescence-Associated Secretory PhenotypeCyclin-Dependent Kinase Inhibitor p21Tumor Suppressor Protein p53Cyclin-Dependent Kinase Inhibitor p16beta-Galactosidase
Top Compounds — Cellular Senescence (50 of 1,484)
1,000
studies
73.3
evidence
1,000
studies
76.1
evidence
1,000
studies
80.1
evidence
1,000
studies
70.5
evidence
1,000
studies
79.5
evidence
1,000
studies
74.1
evidence
1,000
studies
75.4
evidence
996
studies
73.3
evidence
9
Syzygium_aromaticum
500
studies
37.4
evidence
10
Brassica_campestris
500
studies
40.0
evidence
11
Solanum_nigrum
500
studies
36.7
evidence
12
Withania_somnifera
500
studies
37.6
evidence
13
Azadirachta_indica
500
studies
37.0
evidence
14
500
studies
43.1
evidence
15
Juglans_regia
500
studies
38.7
evidence
16
Momordica_charantia
500
studies
38.6
evidence
17
Neuropeptide_y
500
studies
44.2
evidence
18
Ocimum_sanctum
500
studies
38.1
evidence
19
Phoenix__dactylifera
500
studies
38.3
evidence
20
Phoenix_dactylifera
500
studies
38.3
evidence
21
Prunus_avium
500
studies
42.2
evidence
22
Psoralea_corylifolia
500
studies
37.1
evidence
23
Cajanus_cajan
500
studies
39.9
evidence
24
Cannabis_sativa
500
studies
39.8
evidence
25
Cucumis_melo
500
studies
41.4
evidence
26
Cucumis_sativus
500
studies
40.0
evidence
27
Curcuma_longa
500
studies
39.8
evidence
28
Cynodon_dactylon
500
studies
40.5
evidence
29
Eucalyptus_globulus
500
studies
39.6
evidence
30
Hibiscus_sabdariffa
500
studies
41.3
evidence
31
Nelumbo__nucifera
500
studies
39.5
evidence
32
Nelumbo_nucifera
500
studies
39.5
evidence
33
Portulaca_oleracea
500
studies
38.3
evidence
34
Raphanus_sativus
500
studies
38.0
evidence
35
Vitis_vinifera
500
studies
40.1
evidence
36
Tinospora_cordifolia
499
studies
38.1
evidence
37
Centella_asiatica
499
studies
38.9
evidence
38
Lens_culinaris
499
studies
43.8
evidence
39
Trigonella_foenum
499
studies
39.0
evidence
40
Boswellia_serrata
499
studies
47.2
evidence
41
Coriandrum_sativum
499
studies
37.6
evidence
42
Nigella_sativa
499
studies
41.7
evidence
43
Foeniculum_vulgare
499
studies
38.5
evidence
44
Linum_usitatissimum
499
studies
41.4
evidence
45
Ricinus_communis
499
studies
37.5
evidence
46
Bacopa_monnieri
498
studies
40.3
evidence
47
Ki_67_antigen
300
studies
50.6
evidence
300
studies
43.3
evidence
49
Shelterin_complex
300
studies
44.3
evidence
50
300
studies
37.9
evidence
Data from PubMed, BindingDB, and Reactome. Not medical advice.