What compounds affect the Amine Oxidase reactions pathway?

40 compounds in the BiohacksAI corpus have documented interactions with genes in the Amine Oxidase reactions pathway (Reactome ID: R-HSA-140179). These compounds target 4 genes within this pathway.

What genes are in the Amine Oxidase reactions pathway?

The Amine Oxidase reactions pathway involves 4 genes. Key genes include: MAOA, MAOB, PAOX, SMOX.

Amine Oxidase reactions

REACTOME PATHWAY

Reactome: R-HSA-1401794 genes40 compounds

The Amine Oxidase reactions pathway (Reactome ID: R-HSA-140179) involves 4 genes and is affected by 40 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

MAOA MAOB PAOX SMOX

Compounds Affecting Amine Oxidase reactions

#	Compound	Targets Hit	Studies
1	Iproniazid	—	300
2	Moclobemide	—	299
3	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
4	Phenelzine	—	297
5	Genistein	—	300
6	Idazoxan	—	300
7	hispidol	—	13
8	Linezolid	—	298
9	Vitamin K 3	—	300
10	chrysin	—	300
11	auraptene	—	148
12	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
13	Fentanyl	—	300
14	Rilmenidine Oxazole derivative that acts as	—	300
15	Chlorhexidine	—	299
16	Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is	—	300
17	Quercetin	—	300
18	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
19	Harmaline	—	300
20	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	—	300
21	Methylene Blue	—	200
22	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
23	plumbagin [Supplementary Concept]	—	300
24	Sirolimus	—	300
25	Rutin	—	300
26	Aripiprazole	—	298
27	Famotidine	—	296
28	Guanabenz	—	298
29	Guanfacine	—	294
30	juglone hydroxylase [Supplementary Concept] catalyzes	—	279
31	Lynestrenol	—	299
32	1-(5,8-dihydro-1,4-dihydroxy-5,8-dioxo-2-naphthyl)-4-methylpent-3-en-1-yl cinnamate [Supplementary Concept]	—	54
33	pentamidine	—	299
34	Sorafenib	—	300
35	Pioglitazone	—	297
36	Farnesol	—	300
37	Zonisamide	—	297
38	Troglitazone	—	299
39	Resveratrol	—	298
40	Spermine	—	300

About the Amine Oxidase reactions Pathway

The Amine Oxidase reactions pathway is catalogued in Reactome (ID: R-HSA-140179) and involves 4 genes. In the BiohacksAI corpus, 40 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MAOA, MAOB, PAOX, SMOX.