What compounds affect the vRNA Synthesis pathway?

16 compounds in the BiohacksAI corpus have documented interactions with genes in the vRNA Synthesis pathway (Reactome ID: R-HSA-192814). These compounds target 1 genes within this pathway.

What genes are in the vRNA Synthesis pathway?

The vRNA Synthesis pathway involves 1 genes. Key genes include: PARP1.

vRNA Synthesis

REACTOME PATHWAY

Reactome: R-HSA-1928141 genes16 compounds

The vRNA Synthesis pathway (Reactome ID: R-HSA-192814) involves 1 genes and is affected by 16 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

PARP1

Compounds Affecting vRNA Synthesis

#	Compound	Targets Hit	Studies
1	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
2	Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent	—	299
3	Bortezomib	—	300
4	Camptothecin	—	300
5	Clofarabine	—	298
6	Daunorubicin	—	298
7	Demecolcine	—	246
8	Epirubicin	—	300
9	Gemcitabine	—	300
10	Homoharringtonine Semisynthetic derivative of harringtonine that acts as	—	300
11	Irinotecan	—	298
12	Nocodazole Nocodazole is	—	215
13	Podophyllotoxin	—	14
14	Teniposide	—	299
15	Thapsigargin	—	300
16	Trabectedin	—	297

About the vRNA Synthesis Pathway

The vRNA Synthesis pathway is catalogued in Reactome (ID: R-HSA-192814) and involves 1 genes. In the BiohacksAI corpus, 16 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PARP1.