Chemokine receptors bind chemokines
REACTOME PATHWAYThe Chemokine receptors bind chemokines pathway (Reactome ID: R-HSA-380108) involves 7 genes and is affected by 19 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Chemokine receptors bind chemokines
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Calcimycin | — | 216 |
| 2 | Disulfiram | — | 297 |
| 3 | Oxyphenbutazone | — | 300 |
| 4 | Quercetin | — | 300 |
| 5 | Clotrimazole | — | 296 |
| 6 | Colchicine | — | 300 |
| 7 | Vitamin | — | 295 |
| 8 | Bromodeoxyuridine | — | 300 |
| 9 | Dacarbazine | — | 299 |
| 10 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | — | 300 |
| 11 | Ethinyl Estradiol | — | 300 |
| 12 | Indomethacin | — | 297 |
| 13 | Retinaldehyde | — | 300 |
| 14 | Tolmetin | — | 298 |
| 15 | Toxaphene | — | 299 |
| 16 | Sphingosine | — | 300 |
| 17 | Perphenazine | — | 297 |
| 18 | Tolterodine Tartrate | — | 73 |
| 19 | hydroxyfasudil [Supplementary Concept] | — | 11 |
About the Chemokine receptors bind chemokines Pathway
The Chemokine receptors bind chemokines pathway is catalogued in Reactome (ID: R-HSA-380108) and involves 7 genes. In the BiohacksAI corpus, 19 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCL2, CCR4, CCR6, CX3CR1, CXCL8.