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BiohacksAI

Evidence-Based Biohacking

Patent Pending

Chemokine receptors bind chemokines

REACTOME PATHWAY
Reactome: R-HSA-3801087 genes19 compounds

The Chemokine receptors bind chemokines pathway (Reactome ID: R-HSA-380108) involves 7 genes and is affected by 19 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CCL2CCR4CCR6CX3CR1CXCL8CXCR1CXCR6

Compounds Affecting Chemokine receptors bind chemokines

#CompoundTargets HitStudies
1Calcimycin216
2Disulfiram297
3Oxyphenbutazone300
4Quercetin300
5Clotrimazole296
6Colchicine300
7Vitamin295
8Bromodeoxyuridine300
9Dacarbazine299
10Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as300
11Ethinyl Estradiol300
12Indomethacin297
13Retinaldehyde300
14Tolmetin298
15Toxaphene299
16Sphingosine300
17Perphenazine297
18Tolterodine Tartrate73
19hydroxyfasudil [Supplementary Concept]11

About the Chemokine receptors bind chemokines Pathway

The Chemokine receptors bind chemokines pathway is catalogued in Reactome (ID: R-HSA-380108) and involves 7 genes. In the BiohacksAI corpus, 19 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCL2, CCR4, CCR6, CX3CR1, CXCL8.