What compounds affect the Biosynthesis of DPAn-3-derived maresins pathway?

37 compounds in the BiohacksAI corpus have documented interactions with genes in the Biosynthesis of DPAn-3-derived maresins pathway (Reactome ID: R-HSA-9026290). These compounds target 2 genes within this pathway.

What genes are in the Biosynthesis of DPAn-3-derived maresins pathway?

The Biosynthesis of DPAn-3-derived maresins pathway involves 2 genes. Key genes include: ALOX12, ALOX5.

Biosynthesis of DPAn-3-derived maresins

REACTOME PATHWAY

Reactome: R-HSA-90262902 genes37 compounds

The Biosynthesis of DPAn-3-derived maresins pathway (Reactome ID: R-HSA-9026290) involves 2 genes and is affected by 37 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

ALOX12 ALOX5

Compounds Affecting Biosynthesis of DPAn-3-derived maresins

#	Compound	Targets Hit	Studies
1	Quercetin	—	300
2	Masoprocol	—	300
3	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
4	butein	—	158
5	piceatannol	—	300
6	fisetin	—	78
7	Tyrosine	—	43
8	Tyrosine	—	300
9	celastrol	—	300
10	Chlorhexidine	—	299
11	Ciclopirox	—	88
12	Diiodotyrosine	—	300
13	Disulfiram	—	297
14	Epinephrine	—	299
15	Flecainide	—	297
16	Fomepizole	—	298
17	Gliclazide	—	300
18	Hexachlorophene	—	300
19	isoetharine	—	112
20	Kynurenic Acid	—	300
21	mg624	—	3
22	Phenelzine	—	297
23	Piribedil	—	300
24	Procarbazine	—	299
25	Rimonabant	—	300
26	scriptaid	—	53
27	Dipyrone	—	298
28	ethopropazine hydrochloride	—	2
29	pterostilbene	—	299
30	Celecoxib	—	295
31	caffeic acid	—	300
32	Kaempferols	—	300
33	Resveratrol	—	298
34	Anthralin	—	299
35	Bufexamac	—	137
36	Indomethacin	—	297
37	Leukotriene A4 (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid.	—	300

About the Biosynthesis of DPAn-3-derived maresins Pathway

The Biosynthesis of DPAn-3-derived maresins pathway is catalogued in Reactome (ID: R-HSA-9026290) and involves 2 genes. In the BiohacksAI corpus, 37 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ALOX12, ALOX5.