An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Leukotriene A4 has been studied across 14 research domains including 🫁 Liver & Detox, 🔬 Inflammation, 🫁 Respiratory, 🔬 Oncology, 🧠 Focus & Attention. The primary research focus is 🫁 Liver & Detox with 12% of studies addressing this area.
The following compounds share molecular targets with Leukotriene A4, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Leukotriene A4 is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.