Question 1

What compounds affect the Signaling by CSF1 (M-CSF) in myeloid cells pathway?

Accepted Answer

38 compounds in the BiohacksAI corpus have documented interactions with genes in the Signaling by CSF1 (M-CSF) in myeloid cells pathway (Reactome ID: R-HSA-9680350). These compounds target 13 genes within this pathway.

Question 2

What genes are in the Signaling by CSF1 (M-CSF) in myeloid cells pathway?

Accepted Answer

The Signaling by CSF1 (M-CSF) in myeloid cells pathway involves 13 genes. Key genes include: CSF1R, FYN, GRB2, HCK, INPPL1, LYN, PIK3CB, PIK3CD, PIK3R1, SRC.

#	Compound	Targets Hit	Studies
1	Dasatinib	—	299
2	Crizotinib	—	298
3	Sorafenib	—	300
4	tyrphostin ag 1478	—	4
5	pictilisib	—	25
6	kenpaullone	—	8
7	Quercetin	—	300
8	alsterpaullone	—	12
9	Wortmannin	—	300
10	ly294002	—	11
11	alpelisib	—	227
12	Sirolimus	—	300
13	Axitinib	—	298
14	Resveratrol	—	298
15	Afatinib	—	297
16	Niclosamide	—	299
17	egcg	—	300
18	sp600125	—	117
19	torin 1	—	10
20	Kaempferols	—	300
21	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
22	Cladribine	—	297
23	Pioglitazone	—	297
24	Vemurafenib	—	298
25	Adenosine Monophosphate Adenine nucleotide containing	—	300
26	monorden	—	8
27	Rosmarinic Acid	—	300
28	Genistein	—	300
29	Acetic Acid Product of	—	300
30	Ku 0063794 [Supplementary Concept]	—	7
31	Budesonide	—	1,000
32	Methylene Blue	—	200
33	Flurandrenolone	—	65
34	Hexachlorophene	—	300
35	streptonigrin	—	299
36	Fingolimod Hydrochloride	—	56
37	Celecoxib	—	295
38	Dactinomycin	—	297

BiohacksAI

Signaling by CSF1 (M-CSF) in myeloid cells

Genes in this Pathway

Compounds Affecting Signaling by CSF1 (M-CSF) in myeloid cells

About the Signaling by CSF1 (M-CSF) in myeloid cells Pathway