A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)
12 Hydroxy 5 8 10 14 Eicosatetraenoic Acid has been studied across 15 research domains including 🔬 Inflammation, ✨ Skin & Hair, 🔥 Metabolic, 🦴 Bone & Joint, 🫘 Kidney. The primary research focus is 🔬 Inflammation with 28% of studies addressing this area.
This evidence profile for 12 Hydroxy 5 8 10 14 Eicosatetraenoic Acid is generated deterministically from 101 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.