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12 Hydroxy 5 8 10 14 Eicosatetraenoic Acid

A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)

101+ PubMed studies analyzed · 1 RCTs · Evidence Score: 43.2

Research Domains

12 Hydroxy 5 8 10 14 Eicosatetraenoic Acid has been studied across 15 research domains including 🔬 Inflammation, ✨ Skin & Hair, 🔥 Metabolic, 🦴 Bone & Joint, 🫘 Kidney. The primary research focus is 🔬 Inflammation with 28% of studies addressing this area.

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This evidence profile for 12 Hydroxy 5 8 10 14 Eicosatetraenoic Acid is generated deterministically from 101 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.