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Aconitine

A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM; DELPHINIUM and larkspurs. It activates VOLTAGE-GATED SODIUM CHANNELS. It has been used to induce ARRHYTHMIAS in experimental animals and it has anti-inflammatory and anti-neuralgic properties.

300+ PubMed studies analyzed · Evidence Score: 37.8

Research Domains

Aconitine has been studied across 19 research domains including ❤️ Cardiovascular, 🦴 Bone & Joint, 🔬 Oncology, 🫁 Liver & Detox, 🧠 Focus & Attention. The primary research focus is ❤️ Cardiovascular with 26% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Aconitine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Bupivacaine
2 shared targets
Lidocaine
2 shared targets
mexiletine
2 shared targets
Veratridine
2 shared targets
tetrodotoxin
2 shared targets
pf
2 shared targets
Saxitoxin
2 shared targets
bdb
2 shared targets
bdb
2 shared targets
Dibucaine
2 shared targets
Loading evidence profile...

This evidence profile for Aconitine is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.